{"title":"HPLC guard columns","description":"\u003cstyle\u003e\n.lx-sub div[title]:hover img, .lx-sub img[src*=\"\/cdn\/shop\/files\/\"]:hover { filter: none !important; opacity: 1 !important; }\n\u003c\/style\u003e\n\u003cdiv class=\"lx-sub\" style=\"text-align: left;\"\u003e\n\u003ch2 style=\"font-size: 1.5rem; font-weight: 600; letter-spacing: -0.02em; line-height: 1.25; color: #0e1a22; margin: 0 0 0.65em;\"\u003eBuy HPLC guard columns online\u003c\/h2\u003e\n\u003cp style=\"font-size: 1.0625rem; line-height: 1.6; color: #0e1a22; margin: 0 0 1.1em;\"\u003eThe HPLC guard columns shelf sits in HPLC columns \u0026amp; accessories. Luminix Health supplies this range from a catalogue of 150.000 laboratory articles for hospitals, universities, pharma and industrial laboratories.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 2.6em;\"\u003e\u003ca href=\"\/en-be\/pages\/get-a-quote\" style=\"display: inline-block; background: linear-gradient(135deg, #0a3d7a, #0e6b8f 48%, #14a0b0); color: #ffffff; font-size: 14px; font-weight: 600; letter-spacing: 0.01em; line-height: 50px; padding: 0 26px; border-radius: 999px; text-decoration: none; box-shadow: 0 8px 20px rgba(10, 61, 122, 0.22);\"\u003eGet your quote\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2 style=\"font-size: 1.5rem; font-weight: 600; letter-spacing: -0.02em; line-height: 1.25; color: #0e1a22; margin: 0 0 0.65em;\"\u003eBrowse our HPLC guard columns\u003c\/h2\u003e\n\u003cp style=\"margin: 0.95em 0 0.35em; font-size: 15px; font-weight: 600; color: #0e1a22;\"\u003eHPLC guard columns\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 0.2em; line-height: 1;\"\u003e\u003ca href=\"\/en-be\/collections\/hplc-columns\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eHPLC columns\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/hplc-fittings-tubing-and-inline-filters\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eHPLC fittings, tubing \u0026amp; inline filters\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/hplc-accessories\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eHPLC accessories\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0.95em 0 0.35em; font-size: 15px; font-weight: 600; color: #0e1a22;\"\u003eHPLC columns \u0026amp; accessories\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 0.2em; line-height: 1;\"\u003e\u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0.95em 0 0.35em; font-size: 15px; font-weight: 600; color: #0e1a22;\"\u003eMain catalogues\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 1.4em; line-height: 1;\"\u003e\u003ca href=\"\/en-be\/collections\/labware\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eLabware\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/instruments\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eInstruments\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/chemicals\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eChemicals\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/consumables\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eConsumables\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/chromatography\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eChromatography\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/microbiological-media\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eLife Science \u0026amp; Microbiology\u003c\/a\u003e\u003ca href=\"\/en-be\/collections\/safety\" style=\"display: inline-block; margin: 0 6px 8px 0; padding: 8px 14px; border-radius: 999px; background: #e8f6f8; color: #0c5f70; font-size: 14px; font-weight: 600; line-height: 1.3; text-decoration: none;\"\u003eSafety\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"font-size: 16px; line-height: 1.65; color: #3d4a4e; margin: 0 0 1.2em;\"\u003eNot sure which article fits the bench? Tell us the application and the pack size. Our specialists help you find it, including a personal quote for the order.\u003c\/p\u003e\n\u003ch2 style=\"font-size: 1.5rem; font-weight: 600; letter-spacing: -0.02em; line-height: 1.25; color: #0e1a22; margin: 0 0 0.65em;\"\u003eOur brands of HPLC guard columns\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; flex-wrap: wrap; gap: 10px; margin: 0 0 2.6em;\"\u003e\u003cdiv title=\"Macherey-Nagel\" style=\"flex: 1 1 calc(25% - 8px); min-width: 150px; max-width: calc(50% - 5px); box-sizing: border-box; display: flex; align-items: center; justify-content: center; height: 88px; padding: 14px 20px; background: #ffffff; border: 1px solid #e2e8e6; border-radius: 12px;\"\u003e\u003ca class=\"lx-brand-tile\" href=\"\/en-be\/collections\/vendors?q=Macherey-Nagel\" aria-label=\"Macherey-Nagel\"\u003e\u003cimg src=\"https:\/\/www.luminixhealth.com\/cdn\/shop\/files\/macherey-nagel-small_d4cd4891-4386-48b2-8d3e-409bee797ef9.png?v=1774973327\u0026amp;amp;width=400\" alt=\"Macherey-Nagel\" loading=\"lazy\" style=\"display: block; max-width: 100%; max-height: 54px; width: auto; height: auto; margin: 0; filter: grayscale(100%); opacity: 0.7; transition: filter 0.2s ease, opacity 0.2s ease;\"\u003e\u003c\/a\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv style=\"background: linear-gradient(135deg, #0a3d7a, #0e6b8f 48%, #14a0b0); border-radius: 20px; padding: 30px 28px 32px; margin: 0; box-shadow: 0 8px 20px rgba(10, 61, 122, 0.22);\"\u003e\n\u003ch2 style=\"font-size: 1.35rem; font-weight: 600; letter-spacing: -0.02em; line-height: 1.3; color: #ffffff; margin: 0 0 0.6em;\"\u003eLuminix Health, your European distributor for HPLC guard columns\u003c\/h2\u003e\n\u003cp style=\"margin: 0 0 0.8em; font-size: 16px; line-height: 1.6; color: #ffffff;\"\u003eOrder HPLC guard columns from Luminix Health and count on:\u003c\/p\u003e\n\u003cul style=\"list-style: none; margin: 0 0 1.3em; padding: 0; font-size: 15px; line-height: 1.55; color: #ffffff;\"\u003e\n\u003cli style=\"display: flex; align-items: flex-start; margin: 0 0 0.45em; color: #ffffff;\"\u003e\n\u003cspan style=\"flex: 0 0 auto; display: inline-block; width: 20px; height: 20px; line-height: 20px; border-radius: 50%; background: #ffffff; color: #0e6b8f; font-size: 12px; font-weight: bold; text-align: center; margin: 2px 10px 0 0;\"\u003e✓\u003c\/span\u003e\u003cspan\u003ePersonal contact and professional advice\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"display: flex; align-items: flex-start; margin: 0 0 0.45em; color: #ffffff;\"\u003e\n\u003cspan style=\"flex: 0 0 auto; display: inline-block; width: 20px; height: 20px; line-height: 20px; border-radius: 50%; background: #ffffff; color: #0e6b8f; font-size: 12px; font-weight: bold; text-align: center; margin: 2px 10px 0 0;\"\u003e✓\u003c\/span\u003e\u003cspan\u003eFast answers and shipping from the heart of Europe, delivery across the EU, two to five days if in stock\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"display: flex; align-items: flex-start; margin: 0 0 0.45em; color: #ffffff;\"\u003e\n\u003cspan style=\"flex: 0 0 auto; display: inline-block; width: 20px; height: 20px; line-height: 20px; border-radius: 50%; background: #ffffff; color: #0e6b8f; font-size: 12px; font-weight: bold; text-align: center; margin: 2px 10px 0 0;\"\u003e✓\u003c\/span\u003e\u003cspan\u003eCompetitive prices and a 24\/7 online range\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"display: flex; align-items: flex-start; margin: 0; color: #ffffff;\"\u003e\n\u003cspan style=\"flex: 0 0 auto; display: inline-block; width: 20px; height: 20px; line-height: 20px; border-radius: 50%; background: #ffffff; color: #0e6b8f; font-size: 12px; font-weight: bold; text-align: center; margin: 2px 10px 0 0;\"\u003e✓\u003c\/span\u003e\u003cspan\u003eA complete assortment of laboratory equipment and supplies\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"margin: 0 0 1.1em; font-size: 16px; line-height: 1.6; color: #ffffff;\"\u003e\u003cstrong\u003eGet in touch for a quote tailored to your laboratory's needs.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003ca href=\"\/en-be\/pages\/get-a-quote\" style=\"display: inline-block; background: #ffffff; color: #0a3d7a; font-size: 14px; font-weight: 600; letter-spacing: 0.01em; line-height: 50px; padding: 0 26px; border-radius: 999px; text-decoration: none;\"\u003eRequest your quote\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","products":[{"product_id":"vp-guard-column-holder-16-mm-short","title":"VP Guard column holder 16 mm (short)","description":"\u003cp\u003eVP guard column holder 16 mm (short) is a VarioPrep short-format holder made for 16 mm internal-diameter guard column cartridges of type VP 10\/16. It positions the guard cartridge upstream of the main column so that particulates and strongly retained matrix components are intercepted before they reach the preparative bed. Packaged as one piece, the holder is recommended for VarioPrep separation columns with 16 or 21 mm ID and fits standard VarioPrep configurations used in preparative HPLC. This component from manufacturer Macherey-Nagel supports laboratories that need dependable guard-column mounting on mid-bore preparative systems. The short construction keeps the flow path compact and simplifies cartridge replacement during method development or routine purification. Choose it when VP 10\/16 guard cartridges must be mounted securely ahead of 16 mm or 21 mm ID VarioPrep columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: VarioPrep short guard column holder\u003c\/li\u003e\n\u003cli\u003eCartridge fit: 16 mm ID VP 10\/16\u003c\/li\u003e\n\u003cli\u003eRecommended for: VarioPrep columns 16 or 21 mm ID\u003c\/li\u003e\n\u003cli\u003eFormat: short holder\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083662\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997112344908,"sku":"718256","price":264.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718256.png?v=1783731129"},{"product_id":"vp-guard-column-holder-32-mm-short","title":"VP Guard column holder 32 mm (short)","description":"\u003cp\u003eVP guard column holder 32 mm (short) is a compact VarioPrep holder for 32 mm internal-diameter guard column cartridges. It is designed for VP 15\/32 cartridges and is recommended for VarioPrep separation columns with 32 and 40 mm ID, providing an upstream guard stage for larger-bore preparative and semi-preparative LC work. The short format keeps the guard assembly space-efficient while still allowing cartridge exchange without disturbing the main column plumbing more than necessary. Supplied as one piece per pack with a net weight of 0,78 kg, the holder suits laboratory HPLC setups that already use the VarioPrep column family. Guard cartridges mounted in this holder help retain particulates and highly retained matrix components before they reach the primary bed, supporting stable separation performance over extended sample sequences. This short 32 mm VP guard column holder from manufacturer Macherey-Nagel addresses users who need a dedicated mount for 32 mm ID cartridges on 32 or 40 mm ID VarioPrep columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: VarioPrep guard column holder (short)\u003c\/li\u003e\n\u003cli\u003eCartridge ID: 32 mm\u003c\/li\u003e\n\u003cli\u003eCompatible cartridges: VP 15\/32\u003c\/li\u003e\n\u003cli\u003eRecommended column ID: 32 and 40 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083686\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997109526860,"sku":"718253","price":480.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718253.png?v=1783731107"},{"product_id":"vp-guard-column-holder-50-mm-short","title":"VP guard column holder 50 mm (short)","description":"\u003cp\u003eVP guard column holder 50 mm (short) is a VarioPrep short-format holder designed for 50 mm internal-diameter guard column cartridges of type VP 15\/50. It supports preparative HPLC workflows by securing the guard cartridge ahead of the main separation column, helping protect the analytical bed and maintain stable chromatographic performance. Supplied as a single piece, the holder is recommended for VarioPrep separation columns from 50 mm ID upward and integrates cleanly into existing VarioPrep hardware setups. This accessory from manufacturer Macherey-Nagel is intended for laboratories running preparative liquid chromatography where reliable guard-column mounting is essential. The compact short design suits space-conscious systems while keeping cartridge exchange straightforward. Use it wherever VarioPrep 50 mm ID guard cartridges must be installed securely before larger-bore preparative columns in routine purification or scale-up work.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: VarioPrep short guard column holder\u003c\/li\u003e\n\u003cli\u003eCartridge fit: 50 mm ID VP 15\/50\u003c\/li\u003e\n\u003cli\u003eRecommended for: VarioPrep columns from 50 mm ID\u003c\/li\u003e\n\u003cli\u003eFormat: short holder\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083679\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997110935884,"sku":"718255","price":750.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718255.png?v=1783731118"},{"product_id":"vp-guard-column-holder-8-mm","title":"VP guard column holder 8 mm","description":"\u003cp\u003eVP guard column holder 8 mm is a VarioPrep accessory for mounting 8 mm internal-diameter guard column cartridges in HPLC systems. It accepts VP 10\/8 guard cartridges and is recommended for VarioPrep separation columns with 8 or 10 mm ID, helping protect the main analytical or preparative column from particulates and strongly retained sample components. The holder is supplied as one piece per pack and integrates into VarioPrep column setups used in method development, routine analysis and preparative chromatography. Compact packaging and a net weight of 0,13 kg support straightforward installation beside the primary column. By placing a matching guard cartridge upstream of the separation column, laboratories can extend column lifetime and maintain chromatographic performance under typical LC operating conditions. This guard column holder from manufacturer Macherey-Nagel is intended for users already working with the VarioPrep platform who need a dedicated 8 mm ID cartridge mount for 8 or 10 mm ID columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: VarioPrep guard column holder\u003c\/li\u003e\n\u003cli\u003eCartridge ID: 8 mm\u003c\/li\u003e\n\u003cli\u003eCompatible cartridges: VP 10\/8\u003c\/li\u003e\n\u003cli\u003eRecommended column ID: 8 or 10 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083693\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997108314444,"sku":"718251","price":280.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718251.png?v=1783731097"},{"product_id":"replacement-wrench-f-guard-column-holde","title":"Replacement wrench f. guard column holde","description":"\u003cp\u003eReplacement spanner for guard column holder is a double open-end wrench prepared for service work on the Column Protection System guard column holder (REF 718966). The tool provides 12 mm and 14 mm openings, allowing controlled tightening and loosening of fittings associated with the precolumn holder during installation, capillary exchange or routine maintenance in liquid chromatography laboratories. Keeping a dedicated spanner with the correct jaw sizes reduces the risk of damaging precision fittings and supports consistent assembly torque practices around the Column Protection System hardware. The spanner is supplied as a single piece and is intended as a practical accessory for chromatography benches and instrument service kits. Suitable for analytical and research environments that maintain modular guard column holders, it complements other replacement parts for the same holder series. This replacement spanner from manufacturer Macherey-Nagel offers a straightforward mechanical aid for laboratories that need reliable tools matched to the Column Protection System precolumn holder during setup, servicing and ongoing LC workflow support.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: Replacement spanner\u003c\/li\u003e\n\u003cli\u003eTool style: Double open-end spanner\u003c\/li\u003e\n\u003cli\u003eOpening sizes: 12 mm and 14 mm\u003c\/li\u003e\n\u003cli\u003eCompatibility: Column Protection System holder REF 718966\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083426\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997139411276,"sku":"718970","price":25.1,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718970.png?v=1783731346"},{"product_id":"o-ring-for-vp-guard-column-holder-16-mm","title":"O-ring for VP guard column holder 16 mm","description":"\u003cp\u003eO-ring 16 mm for VP guard column holder is a sealing spare part intended for the 16 mm VP guard column holder (718256). It replaces worn seals on the corresponding holder so that the guard-column interface can be restored without exchanging the entire assembly. The pack contains two pieces, providing a convenient stock level for routine maintenance of chromatography systems that use 16 mm VP guard column holders. Dimensionally matched to the specified holder, the O-ring supports laboratories that standardise on this hardware format for column protection. Manufactured by Macherey-Nagel, the part sits within the broader set of chromatography accessories used to keep guard-column setups serviceable. Analytical groups running HPLC and related separation methods benefit from having correct-size seals available when holders are opened for cartridge or frit service. The two-piece pack is suitable for instrument benches and central laboratory stores that maintain VP guard column holder fleets at the 16 mm size.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 2 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: O-ring for VP guard column holder\u003c\/li\u003e\n\u003cli\u003eSize: 16 mm\u003c\/li\u003e\n\u003cli\u003eCompatible holder: 718256\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083396\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997143081292,"sku":"718976","price":179.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718976.png?v=1783731374"},{"product_id":"o-ring-for-vp-guard-column-holder-32-mm","title":"O-ring for VP guard column holder 32 mm","description":"\u003cp\u003eO-ring 32 mm for VP guard column holder is a dedicated sealing spare for preparative chromatography setups that use matching 32 mm VP guard column holders. Designed as a direct replacement component, it restores a reliable seal between holder parts so mobile phase and sample streams remain contained during method development, purification, and routine column protection work. The ring is intended for Vorsäulenhalter units referenced as 718252 and 718253, making it straightforward to keep critical guard-column hardware serviceable without exchanging the full holder assembly. Supplied in a practical pack of two pieces, the accessory supports laboratories that maintain multiple systems or prefer a ready spare on hand. Offered from manufacturer Macherey-Nagel within the chromatography accessories range, this O-ring helps preserve leak-tight connections around VP guard column holders used upstream of analytical or preparative columns. Compact packaging and low net weight simplify storage beside HPLC and related liquid-chromatography equipment. Choose this 32 mm format when your VP guard column holder specification calls for the corresponding sealing diameter and a two-piece pack for continuous laboratory operation.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 2 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: O-ring for VP guard column holder\u003c\/li\u003e\n\u003cli\u003eDiameter: 32 mm\u003c\/li\u003e\n\u003cli\u003eCompatibility: Guard column holders 718252 and 718253\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083389\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997144129868,"sku":"718977","price":205.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718977.png?v=1783731383"},{"product_id":"o-ring-for-vp-guard-column-holder-50-mm","title":"O-ring for VP guard column holder 50 mm","description":"\u003cp\u003eO-ring 50 mm for VP guard column holder is a replacement sealing element for larger VP guard column holder formats used in liquid chromatography. It provides the interface seal required on 50 mm Vorsäulenhalter hardware so guard columns remain securely mounted and fluid paths stay tight under normal laboratory operating conditions. The part is specified for holder reference 718255, allowing targeted maintenance when the original seal shows wear or when a spare is needed for system readiness. Delivered as a pack of two pieces, it suits chromatography benches that run parallel purification or protection setups and want minimal downtime for holder service. This accessory from manufacturer Macherey-Nagel belongs to the chromatography accessories portfolio and complements VP guard column holders in preparative and related LC workflows. Low net weight and compact outer packaging support organised storage next to columns, holders, and other HPLC consumables. Select the 50 mm O-ring when your VP guard column holder requires this diameter and a two-piece pack for reliable sealing performance in everyday laboratory chromatography practice.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 2 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: O-ring for VP guard column holder\u003c\/li\u003e\n\u003cli\u003eDiameter: 50 mm\u003c\/li\u003e\n\u003cli\u003eCompatibility: Guard column holder 718255\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083372\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997145506124,"sku":"718978","price":244.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718978.png?v=1783731393"},{"product_id":"o-ring-for-vp-guard-column-holder-8-mm","title":"O-ring for VP guard column holder 8 mm","description":"\u003cp\u003eO-ring 8 mm for VP guard column holder is a sealing spare part designed for the 8 mm VP guard column holder (718251). The ring restores the sealing interface of the holder when the original O-ring shows wear, helping maintain a reliable connection in chromatography guard-column assemblies. Supplied as a pack of two pieces, it gives laboratories a ready reserve for scheduled maintenance or unplanned replacement during instrument upkeep. This accessory is intended for users of VP guard column holders who need dimensionally matched seals rather than full holder replacement. From manufacturer Macherey-Nagel, the 8 mm O-ring belongs to the chromatography accessories range used alongside analytical column-protection hardware. Keeping matching O-rings on hand supports continuous operation of HPLC and related separation systems where guard columns protect the analytical column. The compact pack format suits both central stores and bench-level spare kits in analytical laboratories that standardise on VP holder geometries.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 2 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: O-ring for VP guard column holder\u003c\/li\u003e\n\u003cli\u003eSize: 8 mm\u003c\/li\u003e\n\u003cli\u003eCompatible holder: 718251\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083402\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997141967180,"sku":"718975","price":151.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-718975.png?v=1783731366"},{"product_id":"guard-column-holder-b","title":"Guard column holder B","description":"\u003cp\u003eGuard column holder B is a chromatography accessory designed for separate use of 5 × 3 mm Valco-type HPLC guard columns. It holds short precolumn cartridges of this compact geometry so that protective packing can be exchanged without removing the analytical column from the system. The holder matches the 5 mm length and 3 mm internal-diameter Valco guard format and provides a reliable mechanical and fluidic connection for routine liquid-chromatography setups. Delivered as one piece, it suits laboratories that employ small-format guard cartridges to trap particulates and strongly retained sample components. This holder from manufacturer Macherey-Nagel supports efficient column protection strategies in HPLC methods that specify 5 × 3 mm Valco-type guards. Its dedicated B configuration keeps installation straightforward during method development, system qualification, or daily maintenance. Choose this hardware when a reusable mount for the smaller Valco guard size is needed alongside analytical HPLC columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column holder\u003c\/li\u003e\n\u003cli\u003eHolder type: B\u003c\/li\u003e\n\u003cli\u003eCompatible guard format: 5 × 3 mm Valco-type\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083051\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997176439116,"sku":"719539","price":168.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-719539.png?v=1783731694"},{"product_id":"guard-column-holder-c","title":"Guard column holder C","description":"\u003cp\u003eGuard column holder C is a dedicated accessory for separate mounting of 21 × 4 mm Valco-type HPLC guard columns. It provides a secure mechanical interface so that short precolumn cartridges can be installed independently of the analytical column, simplifying exchange during routine HPLC maintenance. The holder is dimensioned for the 21 mm length and 4 mm internal-diameter Valco guard format and supports stable fluidic connection in standard liquid-chromatography systems. Supplied as a single unit, it is intended for laboratories that protect analytical columns with replaceable guard cartridges of this size. This holder from manufacturer Macherey-Nagel complements matching VA 21\/4 guard columns and helps keep the separation path clean by allowing quick cartridge replacement without disturbing the main column. Compact packaging and a focused design make it a practical hardware component for ion-exchange, organic-acid, and other HPLC methods that rely on Valco-style 21 × 4 mm guards. Use it wherever a reusable holder for this cartridge geometry is required.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 1 pc\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column holder\u003c\/li\u003e\n\u003cli\u003eHolder type: C\u003c\/li\u003e\n\u003cli\u003eCompatible guard format: 21 × 4 mm Valco-type\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681083068\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57997175128396,"sku":"719538","price":256.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-719538.png?v=1783731660"},{"product_id":"ec-42-nucleodur-100-3-c18-ec","title":"EC 4\/2 NUCLEODUR 100-3 C18 ec","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-3 C18 ec is an HPLC guard column for protecting analytical main columns in reversed-phase liquid chromatography. It has a length of 4 mm and an internal diameter of 2 mm, and is intended for use with main columns of 2 mm ID. The NUCLEODUR 100-3 C18 ec packing is a fully endcapped C18 phase on spherical silica, matching the chemistry of corresponding analytical columns so that selectivity remains consistent when the guard is installed upstream. Supplied as a pack of 3 pieces, the cartridges require the Column Protection System guard column holder (REF 718966) for correct mounting. Used as a disposable front-end filter, the guard retains particulates and strongly retained matrix components before they reach the main bed, helping to preserve efficiency and extend column lifetime in routine and method-development work. This EC-format guard column from manufacturer Macherey-Nagel is a practical choice for laboratories running narrow-bore 2 mm ID HPLC systems that need reliable column protection without changing the primary separation phase.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-3 C18 ec\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057441\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998453473612,"sku":"76193120","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_6ef8963a-9c75-4c6a-aced-758b1dc28e90.jpg?v=1791407803"},{"product_id":"ec-42-nucleodur-100-3-c8-ec","title":"EC 4\/2 NUCLEODUR 100-3 C8 ec","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-3 C8 ec is an HPLC guard column developed to shield narrow-bore analytical columns in liquid chromatography applications. Each cartridge is 4 mm long with a 2 mm inner diameter and contains the NUCLEODUR 100-3 C8 ec stationary phase. The product is delivered as a pack of three units and is intended exclusively for main columns with 2 mm internal diameter. A dedicated Column Protection System guard-column holder (REF 718966) is required for correct mounting and leak-free operation. Placed upstream of the analytical column, the guard bed retains particulates and highly retained matrix components, helping to preserve efficiency, back-pressure stability and chromatographic reproducibility. This EC-series precolumn from manufacturer Macherey-Nagel matches the chemistry of corresponding NUCLEODUR C8 ec main columns, facilitating straightforward method continuity in laboratories that rely on compact HPLC formats and consistent C8 selectivity.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eColumn length: 4 mm\u003c\/li\u003e\n\u003cli\u003eInner diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-3 C8 ec\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057403\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998454030668,"sku":"76193620","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_9feecbfe-a470-4af4-90cb-fd8d323e4265.jpg?v=1791407809"},{"product_id":"ec-42-nucleodur-100-3-cn-rp","title":"EC 4\/2 NUCLEODUR 100-3 CN-RP","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-3 CN-RP is an HPLC guard column for protecting analytical main columns in liquid chromatography. With a length of 4 mm and an inner diameter of 2 mm, it is matched to 2 mm ID main columns, capturing particulates and strongly retained matrix components before they enter the analytical packing.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eThe cartridge is filled with the NUCLEODUR 100-3 CN-RP stationary phase, a cyano reversed-phase material suited to methods that benefit from nitrile selectivity. Supplied in packs of three pieces by manufacturer Macherey-Nagel, these EC guard cartridges require the Column Protection System guard column holder (REF 718966) for proper installation. The format supports narrow-bore HPLC workflows where preserving the integrity of sensitive 2 mm ID columns is essential for stable retention, peak shape, and reduced downtime caused by column fouling.\u003c\/p\u003e\n\u003cp\u003eUse cases include method development, routine analysis, and quality-control environments that rely on CN-RP chemistry and need consistent precolumn protection aligned with the main column dimensions and phase type.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-3 CN-RP\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInner diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057366\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998455177548,"sku":"76194120","price":159.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_1cbbabdb-feaf-4f5a-9109-9eb7b6e4009c.jpg?v=1791407815"},{"product_id":"ec-42-nucleodur-100-3-nh2-rp","title":"EC 4\/2 NUCLEODUR 100-3 NH2-RP","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-3 NH2-RP is an HPLC guard column intended to protect analytical main columns during liquid chromatography. The cartridge measures 4 mm in length with a 2 mm internal diameter and is specified for use with main columns of 2 mm ID, helping retain particulates and strongly adsorbed sample components before they reach the analytical bed. Its NUCLEODUR 100-3 NH2-RP phase designation aligns the guard chemistry with corresponding amino reverse-phase separations on matching analytical columns. Each pack contains three guard columns and requires the Column Protection System guard column holder (REF 718966) for correct mounting in the flow path. These EC-format precolumns from manufacturer Macherey-Nagel support routine HPLC method protection where a short, narrow-bore guard is preferred. Matching the 2 mm ID geometry of the main column preserves flow characteristics and chromatographic integrity across analytical runs. The compact EC 4\/2 format integrates readily into HPLC systems configured for 2 mm columns and is supplied ready for installation once the dedicated holder is in place.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-3 NH2-RP\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057328\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998456422732,"sku":"76195120","price":159.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_38009de2-dd7d-4bba-b384-f27e53fa244f.jpg?v=1791407820"},{"product_id":"ec-42-nucleodur-100-5-c18-ec","title":"EC 4\/2 NUCLEODUR 100-5 C18 ec","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-5 C18 ec is an HPLC guard column for protecting narrow-bore analytical columns in reversed-phase liquid chromatography. It offers a length of 4 mm and an internal diameter of 2 mm, and is intended for main columns with 2 mm ID. The NUCLEODUR 100-5 C18 ec packing provides a fully endcapped C18 stationary phase on spherical silica, matching the chemistry of corresponding 5 µm analytical columns so that selectivity stays aligned when the guard is fitted upstream. The product is supplied as a pack of 3 pieces and requires the Column Protection System guard column holder (REF 718966) for installation. As a replaceable front-end element, the guard retains particulates and strongly retained matrix components before they enter the main bed, supporting stable efficiency and longer analytical column lifetime in daily laboratory use. This EC-format guard column from manufacturer Macherey-Nagel is well suited to laboratories operating 2 mm ID HPLC systems that need straightforward column protection without changing the primary separation phase.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-5 C18 ec\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057427\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998453735756,"sku":"76193220","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_35978848-6188-4f7b-bef0-840557dbc5c4.jpg?v=1791407806"},{"product_id":"ec-42-nucleodur-100-5-c8-ec","title":"EC 4\/2 NUCLEODUR 100-5 C8 ec","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-5 C8 ec is an HPLC guard column intended to protect analytical main columns in liquid chromatography. It has a length of 4 mm and an inner diameter of 2 mm, matching the geometry of 2 mm ID main columns so that particulates and strongly retained matrix components are trapped before they reach the analytical bed.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eThe cartridge uses the NUCLEODUR 100-5 C8 ec stationary phase, supporting reversed-phase work based on octyl-bonded silica. Each pack contains three pieces and is supplied by manufacturer Macherey-Nagel. Installation requires the Column Protection System guard column holder (REF 718966), ensuring a secure fit in EC-format systems. This configuration suits narrow-bore HPLC methods where safeguarding sensitive 2 mm ID columns helps maintain peak shape, reduce contamination risk, and limit premature column replacement.\u003c\/p\u003e\n\u003cp\u003eTypical use includes method development, routine analysis, and quality-control workflows that demand stable chromatographic performance and efficient protection of the main separation column under continuous sample load.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-5 C8 ec\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInner diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057380\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998454620492,"sku":"76193720","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_da603a56-4089-43da-bc85-abb9955c3148.jpg?v=1791407812"},{"product_id":"ec-42-nucleodur-100-5-nh2-rp","title":"EC 4\/2 NUCLEODUR 100-5 NH2-RP","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 100-5 NH2-RP is an HPLC guard column (precolumn) for protecting analytical main columns in liquid chromatography. It has a length of 4 mm and an internal diameter of 2 mm, and is intended for main columns with 2 mm ID. The cartridge is packed with the NUCLEODUR 100-5 NH2-RP stationary phase, supporting amino reversed-phase HPLC workflows where front-end protection of the analytical bed is required. Each unit is supplied as a pack of 3 pieces from manufacturer Macherey-Nagel and fits the EC guard format used with compatible column hardware. Installation requires the Column Protection System guard column holder (REF 718966). Placed upstream of the separation column, the guard cartridge helps intercept particulates and strongly retained matrix components before they reach the main packing. The compact EC 4\/2 geometry matches narrow-bore HPLC systems that run 2 mm ID columns and use NUCLEODUR-based NH2-RP chemistry. These replaceable precolumns belong to the HPLC chromatography columns category and serve as consumable protection elements rather than primary separation devices, supporting routine method continuity on matching analytical columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 100-5 NH2-RP\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057298\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998456848716,"sku":"76195320","price":159.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_20778d53-35e9-41f0-9403-e0f0b2860184.jpg?v=1791407825"},{"product_id":"ec-42-nucleodur-300-5-c18-ec","title":"EC 4\/2 NUCLEODUR 300-5 C18 ec","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 300-5 C18 ec is an HPLC guard column (precolumn) for protecting analytical main columns in liquid chromatography. It has a length of 4 mm and an internal diameter of 2 mm and is intended for main columns with 2 mm ID. The cartridge is packed with the NUCLEODUR 300-5 C18 ec stationary phase, a C18 endcapped material suited to reversed-phase HPLC where sample matrix and particulates can shorten column life. Units are supplied in a pack of three and must be used with the Column Protection System guard column holder (REF 718966). Placed upstream of the analytical column, the guard bed retains strongly retained components and debris, helping preserve efficiency, peak shape and system pressure stability. This EC-format guard column from manufacturer Macherey-Nagel fits routine method protection in pharmaceutical, chemical and research laboratories that run narrow-bore 2 mm ID columns. Compact dimensions keep extra-column volume low while supporting reliable day-to-day HPLC operation.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column (precolumn)\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 300-5 C18 ec\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInner diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681056987\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998463172940,"sku":"76198820","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_7e5c0701-cf14-4e27-8751-c9c339c60fdd.jpg?v=1791407869"},{"product_id":"ec-42-nucleodur-300-5-c4-ec","title":"EC 4\/2 NUCLEODUR 300-5 C4 ec","description":"\u003cp\u003eEC 4\/2 NUCLEODUR 300-5 C4 ec is an HPLC guard column (precolumn) for protecting analytical main columns in liquid chromatography systems. It offers a length of 4 mm and an internal diameter of 2 mm and is intended for main columns with 2 mm ID. The cartridge contains the NUCLEODUR 300-5 C4 ec stationary phase, a C4 endcapped packing chosen for reversed-phase applications where less hydrophobic retention than C18 is preferred. Supplied as a pack of three pieces, the guard cartridges require the Column Protection System guard column holder (REF 718966). Positioned before the analytical column, they help retain particulates and strongly retained sample constituents, supporting consistent efficiency, peak integrity and pressure behaviour. This EC-format guard column from manufacturer Macherey-Nagel is suited to pharmaceutical, chemical and research laboratories running narrow-bore 2 mm ID HPLC methods. Compact geometry keeps extra-column contribution low while extending the usable life of the main column.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column (precolumn)\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR 300-5 C4 ec\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInner diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681056963\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998463467852,"sku":"76198920","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_bbf084a2-ed58-458e-b83b-ed9cf5427985.jpg?v=1791407872"},{"product_id":"ec-42-nucleodur-c18-gravity-18-m","title":"EC 4\/2 NUCLEODUR C18 Gravity, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Gravity is an HPLC guard column with 1,8 µm particle size, designed to protect analytical main columns in reversed-phase chromatography. The cartridge measures 4 mm in length with a 2 mm internal diameter and is intended for use with main columns of 2 mm ID. Supplied in a pack of three pieces, these guard columns help extend the lifetime of the analytical column by retaining particulates and strongly retained sample components before they reach the main bed. The NUCLEODUR C18 Gravity phase from manufacturer Macherey-Nagel is a well-established C18 material suited to demanding HPLC separations. Installation requires the Column Protection System guard column holder (REF 718966). Compact EC-format dimensions support straightforward integration into existing HPLC setups where a short, narrow-bore precolumn is preferred. Ideal for laboratories seeking reliable column protection without altering the selectivity of the primary NUCLEODUR C18 Gravity separation.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 Gravity\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length, 2 mm ID\u003c\/li\u003e\n\u003cli\u003eCompatibility: main columns with 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057809\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998446035276,"sku":"76190120","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_64949e1a-0c01-49a8-92b5-da810f5863b2.jpg?v=1791407750"},{"product_id":"ec-42-nucleodur-c18-gravity-3-m","title":"EC 4\/2 NUCLEODUR C18 Gravity, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Gravity is an HPLC guard column packed with 3 µm particles to safeguard analytical main columns in C18 reversed-phase applications. The cartridge is 4 mm long with a 2 mm internal diameter and is specified for main columns of 2 mm ID. Delivered as a pack of three pieces, it supports regular exchange without interrupting laboratory workflows. Placing the guard column ahead of the analytical bed reduces contamination from particulates and strongly retained sample constituents, helping preserve column performance. The NUCLEODUR C18 Gravity phase from manufacturer Macherey-Nagel ensures phase continuity with matching analytical columns. Mounting requires the Column Protection System guard column holder (REF 718966). The short EC geometry keeps system volume low while providing reliable precolumn protection for narrow-bore HPLC methods in analytical and preparative support environments.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 Gravity\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length, 2 mm ID\u003c\/li\u003e\n\u003cli\u003eCompatibility: main columns with 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057786\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998446723404,"sku":"76190220","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_2d7cfbd6-15f9-4a59-88a4-e083459d09e6.jpg?v=1791407753"},{"product_id":"ec-42-nucleodur-c18-gravity-5-m","title":"EC 4\/2 NUCLEODUR C18 Gravity, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Gravity, 5 µm is an HPLC guard column configured for narrow-bore analytical setups. Each cartridge is 4 mm long with a 2 mm internal diameter and contains NUCLEODUR C18 Gravity stationary phase at 5 µm particle size, providing chemical continuity with matching C18 gravity main columns. The product is offered as a pack of three pieces from manufacturer Macherey-Nagel and is specified for main columns with 2 mm internal diameter. Use requires the Column Protection System guard column holder (REF 718966), available separately. Positioned upstream of the analytical column, the guard bed intercepts particulates and highly retained matrix components, helping preserve efficiency, back-pressure stability and service life of the primary column. The EC 4\/2 format suits microbore and narrow-bore HPLC methods where low extracolumn volume and phase-matched protection are essential. Laboratories running NUCLEODUR C18 Gravity separations can deploy these cartridges as a practical consumable for method robustness in research, development and routine analysis.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eColumn length: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C18 Gravity\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057762\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998446985548,"sku":"76190320","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_ccc4b2e2-ed10-45e0-bc11-1386633c0d00.jpg?v=1791407756"},{"product_id":"ec-42-nucleodur-c18-gravity-sb-18-m","title":"EC 4\/2 NUCLEODUR C18 Gravity-SB, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Gravity-SB, 1,8 µm is an HPLC guard column for protecting narrow-bore analytical columns in high-performance liquid chromatography. The cartridge has a length of 4 mm and an internal diameter of 2 mm, packed with NUCLEODUR C18 Gravity-SB material at 1,8 µm particle size. It is supplied as a pack of three pieces and is intended exclusively for main columns with 2 mm internal diameter. Use requires the Column Protection System guard column holder (REF 718966), available separately. By capturing particulates and highly retained matrix components upstream of the analytical bed, the guard cartridge helps maintain peak shape, retention stability and column lifetime in demanding reversed-phase methods. The Gravity-SB C18 chemistry supports modern UHPLC- and HPLC-style separations on matching NUCLEODUR main columns. This EC-series accessory from manufacturer Macherey-Nagel fits laboratories that standardise on 2 mm ID column hardware. Net weight per pack is 0,02 kg. Select this 4 mm × 2 mm format when a NUCLEODUR C18 Gravity-SB, 1,8 µm guard column is specified for narrow-bore column protection.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 Gravity-SB, 1,8 µm\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681056949\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998463729996,"sku":"76199020","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/idl-76199020.png?v=1783731260"},{"product_id":"ec-42-nucleodur-c18-gravity-sb-3-m","title":"EC 4\/2 NUCLEODUR C18 Gravity-SB, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Gravity-SB, 3 µm is an HPLC guard column for protecting analytical main columns in liquid chromatography. It has a length of 4 mm and an internal diameter of 2 mm, and is packed with 3 µm NUCLEODUR C18 Gravity-SB stationary-phase particles. The cartridge is intended for main columns with 2 mm internal diameter, retaining particulates and strongly retained matrix components before they reach the analytical bed and thereby supporting longer main-column service life.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eOffered as a pack of three pieces from manufacturer Macherey-Nagel, these guard columns require the Column Protection System guard-column holder (REF 718966) for correct mounting. The EC format fits narrow-bore HPLC configurations and integrates into standard reversed-phase workflows that use C18 Gravity-SB selectivity. Laboratories running routine analysis or method development can place the cartridge between injector and main column as a replaceable protective interface, matched to 2 mm ID analytical columns for consistent chromatographic performance under everyday laboratory conditions.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 Gravity-SB\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681056925\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998464057676,"sku":"76199120","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_32502bad-ebb3-46de-a1ca-2ef7010a41d3.jpg?v=1791407875"},{"product_id":"ec-42-nucleodur-c18-gravity-sb-5-m","title":"EC 4\/2 NUCLEODUR C18 Gravity-SB, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Gravity-SB, 5 µm is an HPLC guard column for protecting analytical main columns in liquid chromatography applications. It measures 4 mm in length with a 2 mm internal diameter and is packed with 5 µm NUCLEODUR C18 Gravity-SB stationary-phase particles. Intended for main columns with 2 mm internal diameter, the cartridge retains particulate matter and strongly retained contaminants ahead of the analytical bed, helping to maintain separation quality and extend main-column lifetime.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eThe product is supplied as a pack of three pieces from manufacturer Macherey-Nagel and requires the Column Protection System guard-column holder (REF 718966) for mounting. Its EC format supports narrow-bore HPLC systems using C18 Gravity-SB reversed-phase chemistry. Laboratories performing routine analysis or method work can install the guard column between the injector and the main column as a practical, replaceable protective stage, provided the 2 mm ID match to the analytical column is observed for reliable chromatographic operation.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 Gravity-SB\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681056901\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998466482508,"sku":"76199220","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_6c526f9d-09a3-4690-90b4-5c3092ab50c0.jpg?v=1791407878"},{"product_id":"ec-42-nucleodur-c18-htec-18-m","title":"EC 4\/2 NUCLEODUR C18 HTec, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 HTec is an HPLC guard column packed with NUCLEODUR C18 HTec material at a particle size of 1,8 µm. The cartridge measures 4 mm in length with an internal diameter of 2 mm and is intended for analytical main columns with 2 mm internal diameter. Supplied as a pack of three pieces, it requires the Column Protection System guard column holder (REF 718966) for installation. This EC-format precolumn from manufacturer Macherey-Nagel is designed for HPLC chromatography setups that use matching 2 mm ID main columns. Length, internal diameter and particle size follow the EC 4\/2 designation so the guard segment seats correctly in the specified holder. The three-piece pack supports successive replacement of the guard element during ongoing liquid chromatography work while the main column remains in place. It suits laboratories organising column protection around the Column Protection System platform for narrow-bore reversed-phase HPLC with NUCLEODUR C18 HTec chemistry.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 HTec\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057502\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998451999052,"sku":"76192520","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_bb813c40-a96f-4db7-a471-82270083ff86.jpg?v=1791407794"},{"product_id":"ec-42-nucleodur-c18-htec-3-m","title":"EC 4\/2 NUCLEODUR C18 HTec, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 HTec is an HPLC guard column packed with NUCLEODUR C18 HTec material at a particle size of 3 µm. The cartridge measures 4 mm in length with an internal diameter of 2 mm and is intended for analytical main columns with 2 mm internal diameter. Supplied as a pack of three pieces, it requires the Column Protection System guard column holder (REF 718966) for installation. This EC-format precolumn from manufacturer Macherey-Nagel is designed for HPLC chromatography setups that use matching 2 mm ID main columns. Length, internal diameter and particle size follow the EC 4\/2 designation so the guard segment seats correctly in the specified holder. The three-piece pack supports successive replacement of the guard element during ongoing liquid chromatography work while the main column remains in place. It suits laboratories organising column protection around the Column Protection System platform for narrow-bore reversed-phase HPLC with NUCLEODUR C18 HTec chemistry at 3 µm particle size.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 HTec\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057489\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998452359500,"sku":"76192620","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_70c770ef-482c-43c3-a456-e56fbe93f29e.jpg?v=1791407797"},{"product_id":"ec-42-nucleodur-c18-htec-5-m","title":"EC 4\/2 NUCLEODUR C18 HTec, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 HTec, 5 µm is an HPLC guard column developed to shield narrow-bore analytical main columns during reversed-phase separations. It has a length of 4 mm and an internal diameter of 2 mm, and is filled with NUCLEODUR C18 HTec material at a 5 µm particle size. The cartridge is specified for main columns with 2 mm internal diameter and must be used with the Column Protection System guard column holder (REF 718966). Supplied in packs of 3 pieces from manufacturer Macherey-Nagel, these guard columns help prolong the service life of valuable HPLC columns by capturing particles and strongly retained sample components upstream of the analytical bed. The C18 HTec phase is suited to robust reversed-phase applications under typical laboratory HPLC conditions. A practical choice for microbore and 2 mm-ID workflows where reliable precolumn protection, simple cartridge handling and reproducible chromatographic performance are required day to day.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C18 HTec\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057465\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998452916556,"sku":"76192720","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_2f105b51-4880-4e51-a6ed-93eb194b4689.jpg?v=1791407800"},{"product_id":"ec-42-nucleodur-c18-isis-18-m","title":"EC 4\/2 NUCLEODUR C18 ISIS, 1.8 µM","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 ISIS is an HPLC guard column with 1,8 µm particles, built to protect analytical main columns during liquid chromatography. The cartridge has a length of 4 mm and an internal diameter of 2 mm, matching main columns with 2 mm ID. Packed as three pieces per pack, the guard columns intercept particulates and strongly retained sample constituents before they reach the analytical bed, helping preserve column lifetime and peak integrity. The NUCLEODUR C18 ISIS reversed-phase chemistry supports selective C18 separations in pharmaceutical, environmental and research HPLC methods. These cartridges from manufacturer Macherey-Nagel require the Column Protection System guard column holder (REF 718966) for correct mounting. The EC 4\/2 format integrates into standard EC column setups and is intended specifically for 2 mm ID main columns. Used as specified, the guard column contributes to stable back-pressure behaviour and reproducible chromatography by shielding the main packing from matrix load and mechanical stress in routine analytical workflows.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 ISIS\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057687\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998448984396,"sku":"76191020","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_1bd56665-98bb-4ee3-a7f7-99ec786cc31c.jpg?v=1791407768"},{"product_id":"ec-42-nucleodur-c18-isis-3-m","title":"EC 4\/2 NUCLEODUR C18 ISIS, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 ISIS is an HPLC guard column with 3 µm particles, designed to safeguard analytical main columns in liquid chromatography systems. The cartridge measures 4 mm in length with a 2 mm internal diameter and is matched to main columns of 2 mm ID. Supplied in packs of three, these guard columns capture particulates and strongly retained sample species before they enter the analytical bed, helping extend column lifetime and protect chromatographic performance. The NUCLEODUR C18 ISIS stationary phase delivers reversed-phase C18 selectivity for pharmaceutical, environmental and research HPLC methods. Cartridges from manufacturer Macherey-Nagel require the Column Protection System guard column holder (REF 718966) for proper installation. The EC 4\/2 format aligns with standard EC column hardware and is specified for use with 2 mm ID main columns. Correctly mounted, the guard column supports reliable routine operation by limiting mechanical and chemical stress on the primary packing while maintaining consistent flow and separation behaviour.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 ISIS\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057663\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998449279308,"sku":"76191120","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_6dafd69a-e870-4c94-8f2a-64f0ee88528d.jpg?v=1791407771"},{"product_id":"ec-42-nucleodur-c18-isis-5-m","title":"EC 4\/2 NUCLEODUR C18 ISIS, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 ISIS, 5 µm is an HPLC guard column configured for narrow-bore analytical systems. The short cartridge has a length of 4 mm and an internal diameter of 2 mm, and is filled with NUCLEODUR C18 ISIS material at 5 µm particle size to align with matching main columns. Offered in a pack of three units, it is specified for main columns with 2 mm internal diameter and must be mounted in the Column Protection System guard column holder (REF 718966). Placed upstream of the analytical column, the guard segment intercepts sample particulates and strongly adsorbed impurities, supporting consistent chromatography and extended main-column service life. The C18 ISIS bonded phase delivers the steric and hydrophobic selectivity characteristic of this NUCLEODUR line, making the EC 4\/2 format a practical choice for laboratories running 2 mm ID methods. Manufactured by Macherey-Nagel, these guard columns integrate cleanly into existing HPLC setups that already use NUCLEODUR C18 ISIS 5 µm chemistry and require reliable, dimension-matched precolumn protection for routine and research applications.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR C18 ISIS\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057649\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998449508684,"sku":"76191220","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_1bb9eeb2-65a1-4cbd-8842-2d4f258ed8b8.jpg?v=1791407774"},{"product_id":"ec-42-nucleodur-c18-pah-18-m","title":"EC 4\/2 NUCLEODUR C18 PAH, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 PAH is an HPLC guard column with 1,8 µm particles, designed to protect analytical main columns in reversed-phase separations of polycyclic aromatic hydrocarbons and related analytes. The cartridge measures 4 mm in length with a 2 mm internal diameter and is intended for use with main columns of 2 mm ID. Supplied in packs of three pieces, these EC-format guard columns help extend column lifetime by trapping particulates and strongly retained matrix components before they reach the analytical bed. The NUCLEODUR C18 PAH phase from manufacturer Macherey-Nagel is matched to corresponding analytical columns of the same chemistry, supporting consistent selectivity in method development and routine analysis. Installation requires the Column Protection System guard-column holder (REF 718966). Compact dimensions and a three-piece pack make the product practical for laboratories running narrow-bore HPLC workflows that demand reliable precolumn protection without changing separation performance.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C18 PAH\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057199\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998458880332,"sku":"76197020","price":162.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_2a3818bb-0857-4d01-930b-1838154d273a.jpg?v=1791407839"},{"product_id":"ec-42-nucleodur-c18-pyramid-18-m","title":"EC 4\/2 NUCLEODUR C18 Pyramid, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Pyramid, 1,8 µm is an HPLC guard column (precolumn) for protecting analytical main columns in liquid chromatography. It has a length of 4 mm and an inner diameter of 2 mm, and is intended for main columns with 2 mm ID. The cartridge is packed with NUCLEODUR C18 Pyramid stationary phase at a particle size of 1,8 µm, supporting reversed-phase HPLC workflows where column lifetime and stable performance matter. Offered in a pack of 3 pieces from manufacturer Macherey-Nagel, these EC-format guard columns require the Column Protection System guard column holder (REF 718966) for correct mounting. By retaining particulates and strongly retained sample components upstream of the analytical bed, the precolumn helps reduce contamination of the main column and supports more consistent chromatographic results. The EC 4\/2 geometry suits narrow-bore systems that already use matching 2 mm ID NUCLEODUR C18 Pyramid chemistry in method development, QC, and routine analysis.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e. See also \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column (EC format)\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C18 Pyramid\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057625\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998449836364,"sku":"76191520","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_b5f827fd-25e2-41d5-b578-e7b0d2d546ee.jpg?v=1791407777"},{"product_id":"ec-42-nucleodur-c18-pyramid-3-m","title":"EC 4\/2 NUCLEODUR C18 Pyramid, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Pyramid, 3 µm is an HPLC guard column for protecting narrow-bore analytical columns packed with matching C18 Pyramid chemistry. The cartridge length is 4 mm and the inner diameter is 2 mm, making it suitable for main columns with 2 mm ID. It is filled with NUCLEODUR C18 Pyramid material at a 3 µm particle size for reversed-phase liquid chromatography applications. Supplied as a pack of 3 pieces from manufacturer Macherey-Nagel, the guard columns must be used with the Column Protection System guard column holder (REF 718966). Placing this EC precolumn upstream helps trap particles and highly retained sample constituents before they reach the analytical bed, supporting longer column life and more stable system pressure. Laboratories that already run NUCLEODUR C18 Pyramid methods on 2 mm ID hardware can adopt the EC 4\/2, 3 µm format to maintain phase consistency while adding a replaceable protective stage in method development, quality control, and routine HPLC work.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e. See also \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column (EC format)\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C18 Pyramid\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057601\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998450327884,"sku":"76191620","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_48b63c48-5287-4fd5-88d8-f032042fb29f.jpg?v=1791407779"},{"product_id":"ec-42-nucleodur-c18-pyramid-5-m","title":"EC 4\/2 NUCLEODUR C18 Pyramid, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C18 Pyramid, 5 µm is an HPLC guard column designed to shield narrow-bore analytical main columns in reverse-phase chromatography. The cartridge is packed with NUCLEODUR C18 Pyramid stationary phase at 5 µm particle size and measures 4 mm in length with a 2 mm internal diameter. Supplied as a pack of three pieces, it must be used with the Column Protection System guard-column holder (REF 718966). This EC 4\/2 format is specified for main columns with 2 mm internal diameter, supporting microbore and narrow-bore HPLC configurations. By retaining particulates and highly retained sample components before they reach the analytical bed, the guard column helps maintain system performance, peak integrity and column service life. The NUCLEODUR C18 Pyramid phase from manufacturer Macherey-Nagel is appropriate for C18-compatible HPLC applications under standard mobile-phase conditions. These guard cartridges fit established column-protection workflows and leave the selectivity of the main column unchanged while adding a replaceable first line of defence against contamination.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column (EC cartridge)\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C18 Pyramid\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057588\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998450622796,"sku":"76191720","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_e5fdfed3-9828-44d0-974f-5337f3ecf275.jpg?v=1791407783"},{"product_id":"ec-42-nucleodur-c8-gravity-18-m","title":"EC 4\/2 NUCLEODUR C8 Gravity, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C8 Gravity, 1,8 µm is an HPLC guard column cartridge for protecting analytical main columns in liquid chromatography. It combines a 4 mm bed length with a 2 mm internal diameter and is packed with NUCLEODUR C8 Gravity stationary phase at a particle size of 1,8 µm. The format is intended for main columns with 2 mm ID and must be used with the Column Protection System guard column holder (REF 718966). Offered as a pack of three pieces from manufacturer Macherey-Nagel, these EC guard cartridges help retain particulates and strongly adsorbed sample components before they reach the analytical bed, supporting longer column lifetime and more stable chromatographic performance. The octyl-bonded C8 Gravity chemistry suits reversed-phase methods that already rely on matching NUCLEODUR C8 Gravity analytical columns. Compact dimensions and defined particle size make the cartridge straightforward to integrate into existing HPLC or UHPLC setups where short EC-style guards are specified for narrow-bore 2 mm columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e. See also \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C8 Gravity\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eLength × ID: 4 mm × 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057748\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998447313228,"sku":"76190520","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_96949ddc-c22b-4773-8fb3-dde86b5bb699.jpg?v=1791407759"},{"product_id":"ec-42-nucleodur-c8-gravity-3-m","title":"EC 4\/2 NUCLEODUR C8 Gravity, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C8 Gravity, 3 µm is an HPLC guard column cartridge for protecting analytical main columns in liquid chromatography applications. It features a 4 mm length and 2 mm internal diameter and is packed with NUCLEODUR C8 Gravity stationary phase at a 3 µm particle size. The cartridge is intended for main columns with 2 mm ID and requires the Column Protection System guard column holder (REF 718966). Delivered as a pack of three pieces from manufacturer Macherey-Nagel, these EC guards help capture particulates and strongly retained contaminants before they enter the analytical bed, supporting column lifetime and consistent chromatographic results. The octyl-bonded C8 Gravity phase is suited to reversed-phase methods that already use matching NUCLEODUR C8 Gravity analytical columns. Defined 3 µm particles and compact EC dimensions allow straightforward integration into HPLC setups that specify short guard cartridges for narrow-bore 2 mm columns.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e. See also \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C8 Gravity\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eLength × ID: 4 mm × 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057724\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998448460108,"sku":"76190620","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_c3744fa5-d0d9-496c-9cf7-b49d6e542c64.jpg?v=1791407762"},{"product_id":"ec-42-nucleodur-c8-gravity-5-m","title":"EC 4\/2 NUCLEODUR C8 Gravity, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR C8 Gravity, 5 µm is an HPLC guard column for analytical liquid chromatography. The cartridge measures 4 mm in length with an internal diameter of 2 mm and uses NUCLEODUR C8 Gravity stationary phase at a particle size of 5 µm. Each pack contains 3 pieces from manufacturer Macherey-Nagel for laboratories working with reversed-phase HPLC on C8 Gravity chemistry. It is intended for main columns with 2 mm internal diameter and requires the Column Protection System guard column holder (REF 718966). In the EC format, this short precolumn is placed upstream of the analytical column so guard and main column can share the same NUCLEODUR C8 Gravity phase. Length, internal diameter and particle size follow the EC 4\/2 geometry used with corresponding narrow-bore analytical columns. Supplied as three cartridges per pack, the product supports regular exchange of the guard element in routine HPLC work and fits analytical setups that already employ NUCLEODUR C8 Gravity columns with 2 mm internal diameter.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR C8 Gravity\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eLength × ID: 4 mm × 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057700\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998448755020,"sku":"76190720","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_724ed949-2aac-4d29-8280-b7fc41d81004.jpg?v=1791407765"},{"product_id":"ec-42-nucleodur-hilic-18-m","title":"EC 4\/2 NUCLEODUR HILIC, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR HILIC, 1,8 µm is an HPLC guard column for protecting analytical main columns in hydrophilic interaction liquid chromatography. The cartridge measures 4 mm in length with a 2 mm internal diameter and is intended for main columns with 2 mm ID. It is packed with NUCLEODUR HILIC material at 1,8 µm particle size, matching HILIC methods that rely on this phase chemistry for polar analyte retention. Each pack contains 3 pieces and comes from manufacturer Macherey-Nagel in the EC guard format used with compatible holders. Installation requires the Column Protection System guard column holder (REF 718966). Positioned upstream of the analytical column, the guard packing helps capture particulates and strongly retained matrix constituents before they reach the main bed. The EC 4\/2 geometry aligns with narrow-bore HPLC systems operating 2 mm ID columns under HILIC conditions. These precolumns are classified among HPLC chromatography columns and act as consumable front-end protection elements, supporting method continuity on matching NUCLEODUR HILIC analytical columns rather than replacing the primary separation column.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR HILIC, 1,8 µm\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057274\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998457373004,"sku":"76196020","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_f23c4c1c-7773-4600-9d2d-0e47b9648f55.jpg?v=1791407828"},{"product_id":"ec-42-nucleodur-hilic-3-m","title":"EC 4\/2 NUCLEODUR HILIC, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR HILIC is an HPLC guard column with a 3 µm particle size for hydrophilic interaction liquid chromatography. The cartridge measures 4 mm in length with a 2 mm internal diameter and is specified for main columns with 2 mm internal diameter. Supplied in packs of three pieces, these precolumns help shield the analytical column by trapping particulates and strongly retained sample constituents upstream of the primary bed. The NUCLEODUR HILIC phase from manufacturer Macherey-Nagel supports HILIC separations of polar compounds under conventional HPLC operating conditions. Installation requires the Column Protection System guard column holder (REF 718966) to mount the EC-format cartridge correctly. Matching the 2 mm ID geometry to narrow-bore analytical columns keeps dead volume low and method transfer simple. Pharmaceutical, biochemical and routine analytical laboratories can use this guard format to maintain column performance and extend service life in HILIC applications. Defined length, internal diameter and particle size allow clear system setup for everyday HPLC work.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR HILIC\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length, 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057250\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998457700684,"sku":"76196120","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_f494e56c-0478-40fe-b2c1-7e853d7c9bfe.jpg?v=1791407831"},{"product_id":"ec-42-nucleodur-hilic-5-m","title":"EC 4\/2 NUCLEODUR HILIC, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR HILIC, 5 µm is an HPLC guard column for hydrophilic interaction liquid chromatography. It has a length of 4 mm, an internal diameter of 2 mm and a particle size of 5 µm, and is intended for main columns with a matching 2 mm internal diameter. The NUCLEODUR HILIC phase supports retention of polar analytes while the short guard bed traps particulates and strongly retained sample components before they reach the analytical column. Supplied in packs of three pieces from manufacturer Macherey-Nagel, these guard columns require the Column Protection System guard-column holder (REF 718966) for correct installation. The compact EC 4\/2 format fits narrow-bore HILIC workflows used in pharmaceutical, environmental and food analysis. When properly mounted, the guard column helps preserve chromatographic efficiency and extends the service life of the main column under the aqueous–organic mobile-phase conditions typical of HILIC separations, making it a practical protective element for routine and method-development work.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e. See also \u003ca href=\"\/en-be\/collections\/hplc-guard-columns\"\u003eHPLC guard columns\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column EC 4\/2\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR HILIC\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eLength: 4 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057236\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998458159436,"sku":"76196220","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_c8f99e96-cd08-4019-b8f2-38fa2ead5c66.jpg?v=1791407833"},{"product_id":"ec-42-nucleodur-pfp-18-m","title":"EC 4\/2 NUCLEODUR PFP, 1.8 µM","description":"\u003cp\u003eEC 4\/2 NUCLEODUR PFP is an HPLC guard column with a particle size of 1,8 µm, supplied for protection of analytical HPLC main columns. The cartridge length is 4 mm and the internal diameter is 2 mm, matching main columns that have a 2 mm internal diameter. Each pack contains three pieces, so spare cartridges are available for scheduled exchange during routine HPLC maintenance. Installation requires the Column Protection System guard column holder (REF 718966), which positions the guard bed in the flow path ahead of the analytical column. Used in this configuration, the EC 4\/2 cartridge helps retain particulates and strongly retained sample constituents before they reach the primary separation column. The NUCLEODUR PFP phase in this EC guard format comes from manufacturer Macherey-Nagel and is intended for laboratories that run HPLC methods on 2 mm ID columns and need a matched protective cartridge. Keeping a ready stock of these 4 mm × 2 mm guard columns supports continuous operation, simpler column care, and consistent chromatographic workflows whenever the protective bed must be replaced without changing the main NUCLEODUR PFP analytical column.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR PFP\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057168\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998459732300,"sku":"76197520","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_624155b6-09c9-46a3-b503-7a726805c04c.jpg?v=1791407844"},{"product_id":"ec-42-nucleodur-pfp-3-m","title":"EC 4\/2 NUCLEODUR PFP, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR PFP is an HPLC guard column with a particle size of 3 µm, intended to protect analytical HPLC main columns during chromatographic work. The cartridge has a length of 4 mm and an internal diameter of 2 mm and is designed for main columns with a 2 mm internal diameter. Supplied in a pack of three pieces, it provides ready replacements for routine exchange of the protective bed. Installation requires the Column Protection System guard column holder (REF 718966), which seats the guard cartridge in the flow path before the analytical column. Operated in this way, the EC 4\/2 unit helps retain particulates and strongly retained sample material that would otherwise reach the primary column packing. This NUCLEODUR PFP guard format from manufacturer Macherey-Nagel suits laboratories running HPLC methods on 2 mm ID columns and seeking a matched 3 µm protective cartridge. Maintaining a supply of these 4 mm × 2 mm guard columns supports continuous instrument use, simpler column maintenance, and reliable chromatographic workflows when the protective bed needs replacement without changing the main NUCLEODUR PFP analytical column on the system.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR PFP\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057144\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998459994444,"sku":"76197620","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_5ccdc67b-7443-4589-93a1-f020f9d68ca7.jpg?v=1791407847"},{"product_id":"ec-42-nucleodur-pfp-5-m","title":"EC 4\/2 NUCLEODUR PFP, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR PFP, 5 µm is an HPLC guard column intended to protect narrow-bore analytical main columns during liquid chromatography. The precolumn has a length of 4 mm and an internal diameter of 2 mm, and is filled with 5 µm NUCLEODUR PFP packing. It is offered in a pack of 3 pieces and is specified for main columns with 2 mm internal diameter. Use requires the Column Protection System guard column holder (REF 718966). This EC 4\/2 NUCLEODUR PFP guard column from manufacturer Macherey-Nagel matches EC-format HPLC systems that employ 2 mm ID main columns and PFP phase chemistry. Positioned before the analytical column, the short guard bed supports retention of particulates and strongly retained sample constituents. The 4 mm length and 2 mm ID geometry are aligned with narrow-bore EC column configurations used in method work and routine separations. Laboratories operating HPLC with 2 mm ID main columns can mount these precolumns in the designated holder for consistent guard-column protection within the EC Column Protection System.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eColumn length: 4 mm\u003c\/li\u003e\n\u003cli\u003eInternal diameter: 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057120\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998460289356,"sku":"76197720","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_da29e057-6014-4ce3-b34a-592ec974c331.jpg?v=1791407850"},{"product_id":"ec-42-nucleodur-phenyl-hexyl-18-m","title":"EC 4\/2 NUCLEODUR Phenyl-Hexyl, 1.8 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR Phenyl-Hexyl, 1,8 µm is an HPLC guard column cartridge designed to protect analytical main columns in liquid chromatography workflows. The packing uses NUCLEODUR Phenyl-Hexyl stationary phase with a particle size of 1,8 µm, offering phenyl-hexyl selectivity suited to aromatic and moderately polar analytes. Each cartridge measures 4 mm in length with a 2 mm internal diameter and is intended for main columns with 2 mm ID. Supplied in packs of 3 pieces from manufacturer Macherey-Nagel, these EC-format guard columns require the Column Protection System guard column holder (REF 718966) for correct installation. Placing a matching Phenyl-Hexyl guard upstream of the analytical column helps retain particulates and strongly retained matrix components, supporting stable retention, peak shape and column lifetime in routine HPLC and UHPLC methods. The compact EC 4\/2 geometry fits narrow-bore setups where low extra-column volume is important. Use these cartridges as consumable pre-columns whenever sample matrices or mobile-phase conditions place elevated stress on the main Phenyl-Hexyl separation column.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column cartridge\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR Phenyl-Hexyl\u003c\/li\u003e\n\u003cli\u003eParticle size: 1,8 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057045\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998462386508,"sku":"76198520","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_0c8ff80c-97c4-42cf-8e22-7288042b3990.jpg?v=1791407861"},{"product_id":"ec-42-nucleodur-phenyl-hexyl-3-m","title":"EC 4\/2 NUCLEODUR Phenyl-Hexyl, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR Phenyl-Hexyl, 3 µm is an HPLC guard column cartridge built to shield analytical main columns packed with Phenyl-Hexyl phase. It contains NUCLEODUR Phenyl-Hexyl material with a 3 µm particle size in a compact EC body of 4 mm length and 2 mm internal diameter, matched to main columns with 2 mm ID. The pack comprises 3 pieces from manufacturer Macherey-Nagel and must be used with the Column Protection System guard column holder (REF 718966). A correctly dimensioned Phenyl-Hexyl guard retains particulates and highly retained matrix components, helping preserve efficiency, peak symmetry and operating pressure on the downstream analytical column. The 3 µm packing aligns with conventional HPLC particle sizes while the short EC 4\/2 format keeps extra-column contribution low in narrow-bore systems. These cartridges serve as routine consumables in method development and quality-control separations that rely on phenyl-hexyl selectivity, allowing timely replacement without disturbing the main column hardware.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column cartridge\u003c\/li\u003e\n\u003cli\u003ePhase: NUCLEODUR Phenyl-Hexyl\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057021\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998462583116,"sku":"76198620","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_ba81eebe-9a03-4651-92de-b513c4575bb2.jpg?v=1791407864"},{"product_id":"ec-42-nucleodur-phenyl-hexyl-5-m","title":"EC 4\/2 NUCLEODUR Phenyl-Hexyl, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR Phenyl-Hexyl, 5 µm is an HPLC guard column measuring 4 mm in length with an internal diameter of 2 mm. It contains NUCLEODUR Phenyl-Hexyl packing at a particle size of 5 µm and is delivered as a pack of 3 pieces. The cartridge is designed for main columns with 2 mm internal diameter and must be used with the Column Protection System guard column holder (REF 718966). Available from manufacturer Macherey-Nagel, this EC 4\/2 format matches narrow-bore analytical HPLC columns of 2 mm ID. The compact 4 mm bed length and 2 mm ID geometry follow the EC 4\/2 designation of the series, while the 5 µm particles correspond to standard NUCLEODUR Phenyl-Hexyl analytical packings. Laboratories operating 2 mm ID main columns can install the guard column in the designated holder ahead of the analytical column. The three-piece pack allows several replacements during ongoing chromatography without immediate reordering. Dimensions, bonded-phase type and holder requirement are specified for direct integration into compatible EC column-protection systems used in HPLC workflows.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR Phenyl-Hexyl\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057007\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998462943564,"sku":"76198720","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_f9d3c5e3-05ca-4e74-bef3-50eab47b42de.jpg?v=1791407867"},{"product_id":"ec-42-nucleodur-pi2-3-m","title":"EC 4\/2 NUCLEODUR Pi2, 3 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR Pi2, 3 µm is an HPLC guard column configured for narrow-bore analytical systems. The cartridge has a length of 4 mm and an internal diameter of 2 mm, and is filled with NUCLEODUR Pi2 stationary phase at a 3 µm particle size. It is supplied as a pack of three pieces and is intended exclusively for main columns with 2 mm internal diameter. A Column Protection System guard column holder (REF 718966) is required for mounting. Offered by manufacturer Macherey-Nagel, this EC-format precolumn shields the analytical column from particulates and strongly adsorbing matrix components, helping maintain peak shape and system pressure stability during extended HPLC runs. The 2 mm internal diameter matches microbore and narrow-bore main columns, supporting low-volume separations in research, method transfer and routine analysis where a Pi2 selectivity is already established. Three replaceable cartridges per pack allow straightforward exchange whenever back-pressure rise or peak distortion indicates that the guard bed should be renewed, without interrupting the main column installation.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eProduct type: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR Pi2\u003c\/li\u003e\n\u003cli\u003eParticle size: 3 µm\u003c\/li\u003e\n\u003cli\u003eDimensions: 4 mm length × 2 mm ID\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057823\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998445805900,"sku":"76181120","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_5398f5f6-64de-478a-b3ff-040e1cdd0da7.jpg?v=1791407747"},{"product_id":"ec-42-nucleodur-pi2-5-m","title":"EC 4\/2 NUCLEODUR Pi2, 5 µm","description":"\u003cp\u003eEC 4\/2 NUCLEODUR Pi2, 5 µm is an HPLC guard column cartridge with a length of 4 mm and an internal diameter of 2 mm, packed with 5 µm NUCLEODUR Pi2 stationary phase. The short precolumn protects analytical main columns of 2 mm ID by retaining particulates and strongly adsorbed contaminants before they reach the primary bed, helping to preserve efficiency and extend column lifetime. Installation requires a Column Protection System guard-column holder (REF 718966). This EC 4\/2 format from manufacturer Macherey-Nagel is intended for HPLC methods that already use 2 mm internal diameter main columns and matching particle sizes. The 5 µm packing aligns with common analytical dimensions so the guard can be integrated without disrupting established separations. It is supplied in a pack of 3 pieces. Typical use includes pharmaceutical, environmental and research chromatography where costly analytical columns benefit from upstream protection. The compact cartridge format supports straightforward exchange when the guard becomes loaded, maintaining system performance in routine and method-development workflows.\u003c\/p\u003e\n\u003c!-- lx-pdp-inline --\u003e\n\u003cp\u003eThis article is part of \u003ca href=\"\/en-be\/collections\/hplc-columns\"\u003eHPLC columns\u003c\/a\u003e, in \u003ca href=\"\/en-be\/collections\/hplc-columns-and-accessories\"\u003eHPLC columns \u0026amp; accessories\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eKey features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePack size: 3 pc(s)\u003c\/li\u003e\n\u003cli\u003eType: HPLC guard column\u003c\/li\u003e\n\u003cli\u003eDimensions: length 4 mm, ID 2 mm\u003c\/li\u003e\n\u003cli\u003eParticle size: 5 µm\u003c\/li\u003e\n\u003cli\u003eStationary phase: NUCLEODUR Pi2\u003c\/li\u003e\n\u003cli\u003eEAN: 4046681057847\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Macherey-Nagel","offers":[{"title":"Default Title","offer_id":57998445445452,"sku":"76181020","price":156.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0955\/4827\/7068\/files\/HPLC-NUCLEODUR-Vorsaeulen-3-1000Wx1000H_a62691b0-5849-461a-8754-3aa755cf4307.jpg?v=1791407744"}],"url":"https:\/\/www.luminixhealth.com\/en-be\/collections\/hplc-guard-columns.oembed","provider":"Luminix Health","version":"1.0","type":"link"}