Beschreibung
anti-Keratin K17 mouse, monoclonal, Ks17.E3, 50 µg/ml, affinity purified (made by PROGEN), Density (D) ~1 g/cm³, Boiling point (bp) ~100 °C, Storage temp. +4 °C
This antibody portfolio includes a wide range of tissue- & tumor-specific primary antibodies for basic research, product development and analysis of a variety of biological questions. The monoclonal antibodies are perfectly applicable for all cell or tissue biology studies and for the analysis of predictive markers in research.
- High epitope affinity
- Highly specific detection of the target protein
- Unconjugated
- Suitable for e.g. western blot, immunoprecipitation, ELISA & immunofluorescence
Ks 17.E3 represents an excellent marker to distinguish myoepithelial cells (positive for K17) from luminal epithelium of various glands (mammary, sweat, salivary, bronchial, tracheal, laryngeal, esophageal) and benign from malignant forms of e.g. mammary gland tumors. In the epidermis suprabasal staining is found only in cornifying regions and in the outer root sheath of hair follicles. Tested reactivity on cultured cell lines: HeLa, A-431. Tumors specifically detected: benign tumors of mammary gland; most malignant forms of mammary tumors are negative for keratin K17.
Immunohistochemistry (IHC) - frozen: 1:10-1:50Immunohistochemistry (IHC) - paraffin: 1:10-1:50 (microwave treatment recommended)Western Blot (WB): 1:100 (0.5 µg/ml)
| Application | IHC WB |
| Host species | mouse |
| Clonality | monoclonal |
| Reactivity antibody | human rat |
| Purification | Affinity chromatography |
| Conjugate | uncojugated |
| Concentration | 50 µg/ml |
| Isotype | IgG2b |
| Uniprot ID AK | Q04695 (human),Q6IFU8 (rat) |
| Clone | Ks17.E3 |
| Target | Human keratin K17 |