Beschreibung
Guanidine thiocyanate, min. 99 %, for biochemistry, Molar mass (M) 118,16 g/mol, Density (D) 1,29 g/cm³, CAS No. 593-84-0, UN-Nr. 1759, EC No. 209-812-1, Empirical formula C2H6N4S
Highly chaotropic agent that potently destroys the three-dimensional structure of proteins, leading to denaturation. Guanidinium (iso)thiocyanate contains potent anionic as well as cationic groups, that form strong hydrogen bonds. It, therefore, can be used to break protein disulfide bonds as well as to disrupt hydrophobic interactions, and is added during RNA extraction in order to inhibit RNAse activity.
Compliance & Safety Information
Danger
Hazard Statements (H-Phrases)
H302+
H302+ – No description available
H312+
H312+ – No description available
H332
Harmful if inhaled
H314
Causes severe skin burns and eye damage
H412EU
H412EU – No description available
H032
H032 – No description available
Precautionary Statements (P-Phrases)
P260
P260 – No description available
P270
P270 – No description available
P280
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352
IF ON SKIN: Wash with plenty of water.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310
Immediately call a POISON CENTER/doctor.