Description
7-Deaza-7-ethynyl-2'-deoxyadenosine is a modified deoxynucleoside supplied at a minimum purity of 95% for chemical-biology and nucleic-acid research. Its empirical formula is C₁₃H₁₄N₄O₃ and the molar mass is 274,28 g/mol. The 7-deaza scaffold combined with a 7-ethynyl substituent introduces a bioorthogonal alkyne handle while altering base-pairing and stacking behaviour relative to natural 2'-deoxyadenosine. The product is packed as 5 mg in plastic, a practical quantity for oligonucleotide synthesis, click-labelling studies and structure–function investigations of modified DNA. The ethynyl group enables copper-catalysed or strain-promoted azide–alkyne cycloaddition, supporting attachment of fluorophores, biotin or other reporter groups after incorporation. Available from manufacturer Carl ROTH, this building block serves laboratories that require characterised nucleoside analogues with clear molecular specifications. Defined purity and molar mass assist accurate weighing and reaction stoichiometry. The small unit size suits method development, pilot conjugations and specialised applications in probe design and epigenetic or biophysical research without surplus inventory.
This article is part of Coenzymes, nucleotides & vitamins, in Biochemicals & reagents.
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Questions about 7-Deaza-7-ethynyl-2'-deoxyadenosine
What is this article?
7-Deaza-7-ethynyl-2'-deoxyadenosine is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Coenzymes, nucleotides & vitamins, inside Biochemicals & reagents, in Life Science & Microbiology.
Coenzymes, nucleotides and vitamins are the small molecules enzymes and cells consume: NAD, ATP, a vitamin cofactor. Purity, salt form and hydration are the specification, and many are unstable in solution or in the light. The lot is stored as the label says, often cold.
A biochemical is a molecule of life, sold as a reagent: an amino acid, a sugar, a nucleotide, a lipid, an enzyme, an antibiotic. The difference from a bulk chemical is that the use is a biological one, and the impurities that matter are the ones that change that use. An enzyme is specified by activity, not only by mass. An antibiotic is specified by potency. Papers are on PubMed. Structures are on PubChem. Strains and lines that consume these reagents are at ATCC.
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