Description
EC 4/3 NUCLEOSIL 300-5 C8 is an HPLC guard column designed to shield analytical main columns during liquid chromatography. It has a length of 4 mm and an internal diameter of 3 mm and is filled with NUCLEOSIL 300-5 C8 stationary phase for reverse-phase octyl separations. The product is supplied as a pack of three pieces for main columns with 3, 4 or 4,6 mm internal diameter and must be used with the Column Protection System guard column holder (REF 718966). These EC-format precolumns from manufacturer Macherey-Nagel trap particulate matter and highly retained sample constituents upstream of the analytical bed, helping preserve column performance over extended use. The EC 4/3 format matches widely used narrow-bore and standard analytical HPLC column IDs, so method transfer remains straightforward. Chromatographers working with C8-bonded silica can replace cartridges as part of regular maintenance without changing the primary column or holder. The three-unit pack supports continuous laboratory operation and convenient stock rotation in HPLC workflows.
This article is part of HPLC columns, in HPLC columns & accessories.
Key features
- Pack size: 3 pc(s)
- Product type: HPLC guard column
- Stationary phase: NUCLEOSIL 300-5 C8
- Length: 4 mm
- Inner diameter: 3 mm
- EAN: 4046681081439
Recently viewed
You may also like
Browse related categories
Category
Sub-category
Catalogue
Brand
Questions about EC 4/3 NUCLEOSIL 300-5 C8
What is this article?
EC 4/3 NUCLEOSIL 300-5 C8 is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC columns, inside HPLC columns & accessories, in Chromatography equipment.
An HPLC column is specified by the stationary phase, the particle size, the length and the internal diameter. A C18, 5 µm, 150 × 4.6 mm column is a different article from a C18, 3 µm, 100 × 2.1 mm column. The smaller bore belongs on a lower flow. A column has a direction and a pH range.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC fittings, tubing & inline filters, HPLC guard columns and HPLC accessories.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
How does ordering and shipping work?
Luminix Health distributes this article from the heart of Europe. Articles in stock ship within 2–5 business days. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
Which other categories should I open?
The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

