Description
N,N-Dimethylformamide, PEPTIPURE®, min. 99,8 %, for peptide synthesis, Molar mass (M) 73,10 g/mol, Density (D) 0,95 g/cm³, Flash point (flp) 57,5 °C, Boiling point (bp) 153 °C, CAS No. 68-12-2, UN-Nr. 2265, EC No. 200-679-5, Empirical formula C3H7NO
N,N-Dimethylformamide (DMF) is a colourless, polar, aprotic solvent with a high boiling point that is frequently used in peptide synthesis. It is known for its ability to dissolve a wide range of organic and inorganic compounds.
In peptide synthesis, DMF is used to dissolve amino acids and peptide coupling reagents such as N,N'-dicyclohexylcarbodiimide (DCC), which is essential for the formation of peptide bonds. DMF is also commonly used as a solvent for other reagents and additives used in peptide synthesis, e.g. bases such as diisopropylethylamine (DIPEA). The polar, aprotic nature of DMF makes it an excellent solvent for reactions involving polar or charged species. It can also act as a dehydrating agent, helping to remove water from reaction mixtures, which is essential in peptide synthesis where water can compete with the formation of peptide bonds.
Compliance & Safety Information
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Hazard Statements (H-Phrases)
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Questions about N,N-Dimethylformamide, PEPTIPURE®, min. 99,8 %, for peptide synthesis, 500 ml
What is this article?
N,N-Dimethylformamide, PEPTIPURE®, min. 99,8 %, for peptide synthesis, 500 ml is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Analytical grade solvents (p.a.), inside Solvents, in Lab chemicals.
An analytical-grade solvent, often marked p.a., has impurity limits tight enough for classical analysis and for preparing reagents. It is not automatically low enough in UV absorbance for HPLC, and it is not dry enough for a water-sensitive reaction. The grade is the purchase.
A solvent dissolves. The grade says which impurities are low enough for the method. Analytical grade is the ordinary pure solvent. HPLC and LC-MS grades limit the absorbance and the ions that would become peaks or background. A dry solvent has had water removed. A deuterated solvent is for NMR, where the hydrogen signal would otherwise drown the sample. Technical grade is for cleaning and for synthesis that does not need a chromatogram. Identity is on PubChem. Names follow IUPAC. Hazards follow ECHA, the CLP Regulation and REACH.
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The category is Solvents. The sub-category is Analytical grade solvents (p.a.). The catalogue is Lab chemicals.
Shelves beside this one are HPLC & LC-MS grade solvents, Dry & deuterated solvents (NMR, synthesis), Technical & synthesis grade solvents and Green & alternative solvents.
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