N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-, CE phosphoramidite, 5 g

N₄-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a protected deoxycytidine building block for solid-phase oligonucleotide synthesis. Identified by CAS number 154110-40-4 and empirical formula C₄₁H₅₀N₅O₈P, it has a molar mass of 771,86 g/mol. The N₄-acetyl protection on the nucleobase, the acid-labile 5'-O-DMT group and the 3'-cyanoethyl phosphoramidite moiety enable stepwise chain elongation under standard DNA synthesis conditions used in research and diagnostic laboratories. Its defined molecular architecture fits established coupling, capping and oxidation cycles on automated synthesizers as well as manual protocols. Laboratories engaged in gene synthesis, antisense construct preparation or biochemical method development can integrate the reagent into existing phosphoramidite routes without altering core process chemistry. The material is intended for professional laboratory use within the biochemicals segment and should be handled according to institutional practices for moisture-sensitive nucleoside phosphoramidites during dissolution and coupling.

This article is part of Pharmacopoeia reagents & excipients.

Key features

• Purity (HPLC): ≥ 97 %
• Colour: white to yellow
• Form: powder
• ¹H-NMR Spectrum: corresponds to assigned structure
• CAS number: 154110-40-4
• Pack sizes: 5 g, 10 g, 25 g, 50 g
• Empirical formula: C₄₁H₅₀N₅O₈P
• Molar mass: 771,86 g/mol
• Storage temperature: -20 °C
• Product type: CE phosphoramidite
• Technical Information Sheet:
• Safety Data Sheet: