Description
Water with 0.1 % Trifluoroacetic acid is a ready-to-use LC-MS eluent blend supplied in ROTISOLV® LC-MS-Grade quality for demanding chromatographic work. The aqueous matrix carries the empirical formula H₂O, a molar mass of 18,01 g/mol and a density of 1,001 g/cm³, with a boiling point of 100 °C. Trifluoroacetic acid is present at 0.1 %, supporting ion-pairing and peak-shape control in reversed-phase LC-MS separations of peptides, small molecules and other ionisable analytes. Packaged as 2,5 l in glass, the solvent is convenient for routine mobile-phase preparation and instrument reservoirs. This ROTISOLV® grade material from manufacturer Carl ROTH is intended for laboratories that require low-background solvents with defined eluent additives for mass-spectrometric detection. Typical uses include gradient and isocratic LC-MS methods, method development and high-sensitivity analytical workflows where consistent water–TFA composition is essential. The clear physical data and chromatographic focus make it a practical choice for solvent systems with eluent additives in research and quality-control environments.
This article is part of HPLC & LC-MS grade solvents, in Solvents. See also Analytical grade solvents (p.a.).
Key features
- Trifluoroacetic acid (v/v): 0.095-0.105 %
- pH value: 1.8-2.0
- 254 nm: ≤0.01 AU
- 230 nm: ≥85 %
- 210 nm: ≤0.05 AU
- Aluminium (Al): ≤0.05 ppm
- Calcium (Ca): ≤0.05 ppm
- Iron (Fe): ≤0.05 ppm
- Potassium (K): ≤0.05 ppm
- Magnesium (Mg): ≤0.05 ppm
- Pack size: 2,5 l glass
- Empirical formula: H₂O
- Molar mass: 18,01 g/mol
- Density: 1,001 g/cm³
- Boiling point: 100 °C
- Technical Information Sheet:
- Safety Data Sheet:
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Questions about Water with 0.1 % Trifluoroacetic acid, ROTISOLV® LC-MS-Grade, 2.5 l, glass
What is this article?
Water with 0.1 % Trifluoroacetic acid, ROTISOLV® LC-MS-Grade, 2.5 l, glass is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in HPLC & LC-MS grade solvents, inside Solvents, in Lab chemicals.
HPLC grade limits the absorbance and the residue that would appear as peaks or baseline drift. LC-MS grade goes further on metal ions and on particles that would suppress a mass spectrum. A solvent that is only analytical grade is a false economy on an LC-MS system.
A solvent dissolves. The grade says which impurities are low enough for the method. Analytical grade is the ordinary pure solvent. HPLC and LC-MS grades limit the absorbance and the ions that would become peaks or background. A dry solvent has had water removed. A deuterated solvent is for NMR, where the hydrogen signal would otherwise drown the sample. Technical grade is for cleaning and for synthesis that does not need a chromatogram. Identity is on PubChem. Names follow IUPAC. Hazards follow ECHA, the CLP Regulation and REACH.
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The category is Solvents. The sub-category is HPLC & LC-MS grade solvents. The catalogue is Lab chemicals.
Shelves beside this one are Analytical grade solvents (p.a.), Dry & deuterated solvents (NMR, synthesis), Technical & synthesis grade solvents and Green & alternative solvents.
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