Description
HPLC Column NUCLEODUR®, C18 Gravity, 5µm, 125x4mm
Material: stainless steel.
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This high density C18 phase based on high purity NUCLEODUR® silica gel with its endcapping suppresses any unwanted polar interactions between the silica surface and the sample, which makes “Gravity” particularly suitable for the separation of basic and other ionizable analytes. Due to the enhanced pH stability, LC/MS suitability and superior base deactivation (BDS) it is a perfect choice for method development and valuable for RP applications.
Delivery incl. 1x analytical HPLC column, instruction leaflet, certificate of analysis.
Technical Information
| Particle size | 5 µm |
| Pore size | 110 Å |
| L x Ø internal (column) | 125 x 4 mm |
| Column volume | 1.56 ml |
| Endcapped | yes |
| Eluent in column | Acetonitrile - Water |
| Phase | C18 Gravity |
| Surface chemistry | Base deactivated (BDS), High density octadecyl (C18, ODS) modification |
| USP listing | L1 |
| Separation principle | Reversed phase (RP) |
| Column shape | Analytical separation column |
| Column type | HPLC column |
| Particle type | Fully porous particles (FPP) |
| Specific surface according to BET | 340 m²/g |
| Pore volume | 0.9 ml/g |
| Temperature stability | 60 ° C |
| Interactions / retention mechanism | hydrophobic (van der Waals) |
| Pressure stability | 600 bar |
| pH stability | 1,0-11,0 |
| Recommended application(s) | In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development |
| Similar phases | NUCLEOSIL® C18 HD Xterra® RP18 / MS C18 Luna® C18(2) Gemini® Synergi™ Max RP Zorbax® Extend C18 Inertsil® ODS III Purospher® Star RP-18 Hypersil™ BDS |
| Application Database (Macherey-Nagel) | HPLC SPE |