Beschrijving
N₆-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE-fosforamidiet is een 2'-O-MOE-beschermd adenosinereagens voor oligonucleotidesynthese. Het wordt geïdentificeerd door CAS-nummer 251647-53-7, de empirische formule C₅₀H₅₈N₇O₉P en een molaire massa van 932,01 g/mol. De 2'-O-(2-methoxyethyl)-modificatie verbetert de nucleasebestendigheid en bindingsaffiniteit in antisense- en verwante constructen, terwijl N₆-benzoyl-, 5'-O-DMT- en 3'-CE-fosforamidietgroepen conventionele vaste-fase-assemblage mogelijk maken. Onderzoeks- en ontwikkelingslaboratoria kunnen het gebruiken voor therapeutische oligonucleotideprogramma's en het ontwerp van sondes met hoge affiniteit. De gedefinieerde moleculaire parameters bevorderen consistente koppelingsprestaties op geautomatiseerde synthesizers. Deze amidiet behoort tot het assortiment biochemische stoffen voor geavanceerde nucleïnezuurchemische toepassingen.
Dit artikel hoort bij Co-enzymen, nucleotiden & vitaminen, in Biochemische stoffen & reagentia.
Belangrijkste kenmerken
- Analyse: ≥ 95 %
- Kleur: gerapporteerd
- Vorm: gerapporteerd
- CAS-nummer: 251647-53-7
- Verpakkingsgrootten: 5 g, 10 g, 25 g
- Empirische formule: C₅₀H₅₈N₇O₉P
- Molaire massa: 932,01 g/mol
- Producttype: 3'-CE-fosforamidiet
- Technisch informatieblad:
- Veiligheidsinformatieblad:
Compliance & Safety Information
Waarschuwing
Hazard Statements (H-Phrases)
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Questions about N6-benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE-fosforamidiet, 5 g
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