Caffeine anhydrous (BP, Ph. Eur.) pure, pharma grade

Caffeine anhydrous (BP, Ph. Eur.) pure, pharma grade
Content: 5 KGM
Physical Description:
solid
Quality Name: pure, pharma grade
Specification: Assay (Perchl. Ac.) calc. a.d.s.: 98.5-101.5 %
Identity according to Pharmacopoeias: passes test
Melting range (a.d.s.): 234-239°C

?maximum limit of impurities:
Appearance of solution: passes test
Acidity: passes test
Insoluble matter in H2O: passes test
Loss on drying: 0.5%
Residue on ignition (as SO4): 0.1 %
Sulfate (SO4): 0.05%
Related Substances (HPLC):
Individual impurity: 0.10%
Total impurities: 0.1%
Chromatographic purity: passes test
Residual solvents (Ph.Eur/USP): passes test
Heavy metals (as Pb): 0.001%
As: 0.0003 %
Cu: 0.001 %
Fe: 0.002 %
Ni: 0.001 %
Pb: 0.001 %
Residual metals (according to EMEA/CHMP/SWP/4446/2000): Nickel compounds as metal catalyst (class 1C classification) can be present. It is below to 0,2 ppm. It is fully in compliance with the EMEA guideline. :