Description
Fast Oxidation reagent, with ABI(TM) and PolyGen® synthesizer, for DNA synthesis, Density (D) 0,8 g/cm³, Flash point (flp) -21 °C, Boiling point (bp) 65 °C, Storage temp. +15 to +25 °C, UN-Nr. 1993
0,02 M Iode
The phosphite triester linkage formed during oligonucleotide synthesis is of limited stability and has to stabilised. Treatment of the support-bound material with iodine and water in the presence of a weak base oxidizes the phosphite triester into a tetracoordinated phosphate triester, a protected precursor of the naturally occurring phosphate diester internucleosidic linkage.
Compliance & Safety Information
Danger
Hazard Statements (H-Phrases)
H225
Highly flammable liquid and vapour
H302
Harmful if swallowed
H315
Causes skin irritation
H319
Causes serious eye irritation
H335
May cause respiratory irritation
H336
May cause drowsiness or dizziness
H351
Suspected of causing cancer
H373EU
H373EU – No description available
H019
H019 – No description available
Precautionary Statements (P-Phrases)
P210
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P261
P261 – No description available
P280
Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353
IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312
P312 – No description available