Description
ROTI®Histofix ECO Plus, SOLVAGREEN®, Fixing agent without formalin, ready-to-use, Density (D) 1,015 g/cm³, Boiling point (bp) ~100 °C, Storage temp. +15 to +25 °C
All SOLVAGREEN® products as well as further information about the product can also be found in our current flyer Green Chemistry- Alternative Solvents and Products.
ROTI®Histofix ECO Plus is a ready-to-use, aqueous solution on the basis of hexamethylene tetramine. The solution has similar good fixation properties like formaldehyde, but is, unlike formaldehyde, classified as non-toxic.
- Formaldehyde-free, non-toxic fixative
- Good fixation properties
- Optimal working range: pH 4,5-6,0
- No denaturing effect, e.g. shrinkage or crosslinking
- Adequate substitute for formaldehyde
The original morphology of the tissue is preserved during the fixation process. The protein molecules are cross-linked in a reversible way, their structures are preserved. That is especially important for antigen-antibody reactions. Samples are - in contrast to other fixative media - free of artefacts such as shrinkage of tissue or irreversible protein crosslinking. The solution is therefore ideal for immunohistochemistry. All conventional staining processes can be carried out following fixation.
ROTI®Histofix ECO Plus is provided with a fragrance for better identification (<1ppm).
| ROTH for Future | yes |
Compliance & Safety Information
Warning
Hazard Statements (H-Phrases)
Precautionary Statements (P-Phrases)