Description
EC 4/2 NUCLEODUR C18 Pyramid, 3 µm is an HPLC guard column for protecting narrow-bore analytical columns packed with matching C18 Pyramid chemistry. The cartridge length is 4 mm and the inner diameter is 2 mm, making it suitable for main columns with 2 mm ID. It is filled with NUCLEODUR C18 Pyramid material at a 3 µm particle size for reversed-phase liquid chromatography applications. Supplied as a pack of 3 pieces from manufacturer Macherey-Nagel, the guard columns must be used with the Column Protection System guard column holder (REF 718966). Placing this EC precolumn upstream helps trap particles and highly retained sample constituents before they reach the analytical bed, supporting longer column life and more stable system pressure. Laboratories that already run NUCLEODUR C18 Pyramid methods on 2 mm ID hardware can adopt the EC 4/2, 3 µm format to maintain phase consistency while adding a replaceable protective stage in method development, quality control, and routine HPLC work.
This article is part of HPLC columns, in HPLC columns & accessories. See also HPLC guard columns.
Key features
- Pack size: 3 pc(s)
- Product type: HPLC guard column (EC format)
- Stationary phase: NUCLEODUR C18 Pyramid
- Particle size: 3 µm
- Dimensions: length 4 mm, ID 2 mm
- EAN: 4046681057601
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Questions about EC 4/2 NUCLEODUR C18 Pyramid, 3 µm
What is this article?
EC 4/2 NUCLEODUR C18 Pyramid, 3 µm is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatography equipment.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
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Luminix Health distributes this article from the heart of Europe. Delivery across Europe, two to five days when in stock. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

