Description
EC 4/3 NUCLEOSIL 100-5 CN is an HPLC guard column for protecting analytical main columns in liquid chromatography. It has a length of 4 mm and an internal diameter of 3 mm and is packed with NUCLEOSIL 100-5 CN stationary phase. The cyano-bonded silica helps retain particulates and strongly adsorbed matrix components before they reach the primary separation bed, supporting longer analytical column lifetime and more stable chromatographic performance. Each pack contains 3 pieces and is intended for main columns with 3, 4 or 4,6 mm internal diameter. Use requires the Column Protection System guard column holder (REF 718966). This EC 4/3 format from manufacturer Macherey-Nagel fits routine HPLC workflows where reliable precolumn protection is needed for moderately polar analytes under normal-phase or reversed-phase conditions. The compact cartridge design makes replacement straightforward during method maintenance and helps reduce unplanned downtime caused by fouled analytical columns in research and quality-control laboratories.
This article is part of HPLC columns, in HPLC columns & accessories.
Key features
- Pack size: 3 pc(s)
- Product type: HPLC guard column
- Stationary phase: NUCLEOSIL 100-5 CN
- Length: 4 mm
- Internal diameter: 3 mm
- EAN: 4046681081354
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Questions about EC 4/3 NUCLEOSIL 100-5 CN
What is this article?
EC 4/3 NUCLEOSIL 100-5 CN is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatography equipment.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
How does ordering and shipping work?
Luminix Health distributes this article from the heart of Europe. Delivery across Europe, two to five days when in stock. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

