Description
EC 4/3 NUCLEOSIL 50-5 C18 ec is an HPLC guard column designed to protect C18 analytical main columns in reversed-phase liquid chromatography. The cartridge length is 4 mm with an internal diameter of 3 mm and is filled with NUCLEOSIL 50-5 C18 ec material in the EC 4/3 format. Installed upstream of the separation column, it traps particulates and highly retained matrix species before they reach the primary packing, helping to stabilise backpressure and prolong main-column service life. The guard is specified for main columns with 3 mm, 4 mm or 4,6 mm internal diameter and must be used with the Column Protection System guard column holder (REF 718966). Supplied as a pack of three pieces from manufacturer Macherey-Nagel, it suits laboratories running NUCLEOSIL C18 ec methods that need matched inlet protection without altering the established selectivity. The endcapped C18 chemistry of the guard aligns with common reversed-phase workflows in pharmaceutical, environmental and chemical analysis. Compact EC 4/3 geometry allows straightforward integration into existing HPLC systems wherever short precolumns are preferred for routine column safeguarding.
This article is part of HPLC columns, in HPLC columns & accessories.
Key features
- Pack size: 3 pc(s)
- Type: HPLC guard column
- Phase: NUCLEOSIL 50-5 C18 ec
- Length: 4 mm
- Internal diameter: 3 mm
- EAN: 4046681081071
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Questions about EC 4/3 NUCLEOSIL 50-5 C18 ec
What is this article?
EC 4/3 NUCLEOSIL 50-5 C18 ec is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatography equipment.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
How does ordering and shipping work?
Luminix Health distributes this article from the heart of Europe. Delivery across Europe, two to five days when in stock. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

