Description
N,O-Bis(trimethylsilyl)acetamide is a silylation reagent of minimum 98 % purity intended for gas chromatography. Identified by CAS number 10416-59-8 and empirical formula C₈H₂₁NOSi₂, it has a molar mass of 203,43 g/mol and a density of 0,83 g/cm³. The boiling range is 41 to 43 °C and the flash point is 40 °C, data that support safe handling planning in derivatisation workflows. Supplied as 25 g in glass from manufacturer Carl ROTH, the reagent is suited to converting polar functional groups into more volatile trimethylsilyl derivatives prior to GC injection. Analytical laboratories use it for sample preparation in organic, pharmaceutical and environmental GC methods where reproducible silylation is essential. The defined minimum assay and physical constants help method developers specify consistent reagent quality. Packaged for routine bench use, this BSA-type reagent fits standard GC derivatisation protocols without additional formulation steps.
This article is part of Inorganic salts, in Inorganic chemicals.
Key features
Compliance & Safety Information


DangerHazard Statements (H-Phrases)
Precautionary Statements (P-Phrases)
Recently viewed
You may also like
Browse related categories
Category
Sub-category
Catalogue
Brand
Questions about N,O-Bis(trimethylsilyl) acetamide, min. 98 %, for GC, 25 g, glass
What is this article?
N,O-Bis(trimethylsilyl) acetamide, min. 98 %, for GC, 25 g, glass is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Chromatography accessories, inside Vials, caps & septa, in Chromatography equipment.
These are the small chromatography parts that are not a column, a vial or a syringe: vial racks, solvent filters, waste caps, ferrule kits. A solvent inlet filter is what keeps the pump from swallowing particles out of the bottle.
An autosampler vial is the small closed bottle a chromatograph picks up. The neck is crimp, screw or snap, and the cap and the septum have to be that neck. The septum is the part the needle pierces. A soft septum reseals. A septum that is wrong for the solvent swells or sheds particles into the sample. Inserts reduce the volume when the sample is scarce. The separation they feed is described with IUPAC names and PubChem data.
Which category should I open next?
The category is Vials, caps & septa. The sub-category is Chromatography accessories. The catalogue is Chromatography equipment.
Shelves beside this one are Vial caps & septa, Autosampler vials, Crimpers & decappers and Vial inserts.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
How does ordering and shipping work?
Luminix Health distributes this article from the heart of Europe. Articles in stock ship within 2–5 business days. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
Which other categories should I open?
The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

