Description
2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE is een gefluoreerd uridine-fosforamidiet ontworpen voor de bereiding van gemodificeerde oligonucleotiden. Het is geregistreerd onder CAS-nummer 146954-75-8, met de empirische formule C₃₉H₄₆FN₄O₈P en een molaire massa van 748,78 g/mol. De 2'-fluor-substitutie op de suikering is een welbekend structureel motief voor het afstemmen van de duplexstabiliteit en nucleasebestendigheid in synthetische nucleïnezuren. Onderzoeksgroepen die werken aan siRNA, aptameren, diagnostische probes of structuur-activiteitsstudies kunnen deze bouwsteen gebruiken om op specifieke posities 2'-fluoruridine-residuen te introduceren. Afkomstig van fabrikant Carl ROTH, past het fosforamidiet in standaard koppelingsprotocollen zoals gebruikt in biochemische en medicinale chemielaboratoria. Specificatiegegevens met betrekking tot de CAS-identiteit, molecuulformule en verpakkingsgrootte vergemakkelijken methodeoverdracht, inkoop en kwaliteitsdocumentatie zonder ambiguïteit.
Dit artikel hoort thuis in Co-enzymen, nucleotiden & vitaminen, in Biochemicaliën & reagentia.
Belangrijkste kenmerken
- Zuiverheid (HPLC): ≥ 98 %
- Kleur: wit tot lichtgeel
- Vorm: poeder tot kristallijn poeder
- ³¹P-NMR-spectrum: komt overeen met de toegewezen structuur
- ¹H-NMR-spectrum: komt overeen met de toegewezen structuur
- CAS-nummer: 146954-75-8
- Verpakkingsgrootten: 2 g, 5 g, 10 g, 25 g
- Empirische formule: C₃₉H₄₆FN₄O₈P
- Molaire massa: 748,78 g/mol
- Producttype: Fluoruridine-fosforamidiet
- Modificatie: 2'-Fluor
- Technisch informatieblad:
- Veiligheidsinformatieblad:
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Questions about 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE, fosforamidiet, 2 g
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2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE, fosforamidiet, 2 g is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Coenzymes, nucleotides & vitamins, inside Biochemicals & reagents, in Milieux microbiologiques.
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