Beschrijving
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is a protected nucleoside derivative with CAS number 171268-84-1 and empirical formula C₁₆H₂₈N₂O₆Si. It has a molar mass of 372,49 g/mol and combines a 2'-O-methyluridine core with a 3'-O-tert-butyldimethylsilyl protecting group, a pattern widely used in oligonucleotide and nucleoside chemistry. Provided in a 5 g pack, the reagent supports synthetic sequences that require selective silyl protection at the 3'-position together with a methylated 2'-oxygen for stability or downstream coupling strategies. Research groups apply such intermediates in the preparation of modified RNA building blocks, protected nucleoside libraries, and related biochemical probes. Identity and molar-mass data from manufacturer Carl ROTH aid planning of protection–deprotection schemes, analytical control, and reproducible laboratory handling. The defined silicon-containing formula enables clear tracking in multi-step routes typical of nucleic-acid chemistry. This material fits academic and industrial workflows in biochemicals where a well-specified, silyl-protected 2'-O-methyluridine intermediate and convenient pack size are essential for method development and small-scale synthesis.
This article is part of Coenzymes, nucleotides & vitamins, in Biochemicals & reagents.
Key features
- Purity (HPLC): ≥ 97 %
- Colour: white to off-white
- Form: powder
- ¹H-NMR Spectrum: corresponds to assigned structure
- Water content (KF): ≤ 2 %
- CAS number: 171268-84-1
- Pack sizes: 5 g, 10 g
- Empirical formula: C₁₆H₂₈N₂O₆Si
- Molar mass: 372,49 g/mol
- Storage temperature: +2 to +8 °C
- Weight: 0,001 kg
- UNSPSC: 12352200
- Technical Information Sheet:
- Safety Data Sheet:
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Questions about 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
What is this article?
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Co-enzymen, nucleotiden & vitaminen, inside Biochemicaliën & reagentia, in Microbiologische media.
Coenzymes, nucleotides and vitamins are the small molecules enzymes and cells consume: NAD, ATP, a vitamin cofactor. Purity, salt form and hydration are the specification, and many are unstable in solution or in the light. The lot is stored as the label says, often cold.
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