2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE, phosphoramidite, 2 g

Catalog nr. 32L1.2
Carl Roth

Volume: 2 g
Value Packs: 1 piece
Price:
Sale price€252,65
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Description

2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE is a fluorinated uridine phosphoramidite designed for the preparation of modified oligonucleotides. It is registered under CAS number 146954-75-8, with empirical formula C₃₉H₄₆FN₄O₈P and a molar mass of 748,78 g/mol. The 2'-fluoro substitution on the sugar ring is a well-established structural motif for tuning duplex stability and nuclease resistance in synthetic nucleic acids. This grade is Research groups working on siRNA, aptamers, diagnostic probes or structure–activity studies can use the building block to introduce 2'-fluorouridine residues at defined positions. Sourced from manufacturer Carl ROTH, the phosphoramidite fits standard coupling protocols used in biochemical and medicinal-chemistry laboratories. Specification data covering CAS identity, molecular formula and pack size facilitate method transfer, purchasing and quality documentation without ambiguity.

This article is part of Coenzymes, nucleotides & vitamins, in Biochemicals & reagents.

Key features

  • Purity (HPLC): ≥ 98 %
  • Colour: white to light yellow
  • Form: powder to crystalline powder
  • ³¹P-NMR Spectrum: corresponds to assigned structure
  • ¹H-NMR Spectrum: corresponds to assigned structure
  • CAS number: 146954-75-8
  • Pack sizes: 2 g, 5 g, 10 g, 25 g
  • Empirical formula: C₃₉H₄₆FN₄O₈P
  • Molar mass: 748,78 g/mol
  • Product type: Fluorouridine phosphoramidite
  • Modification: 2'-Fluoro
  • Technical Information Sheet: PDF
  • Safety Data Sheet: PDF

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Questions about 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE, phosphoramidite, 2 g

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2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE, phosphoramidite, 2 g is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Coenzymes, nucleotides & vitamins, inside Biochemicals & reagents, in Life Science & Microbiology.

Coenzymes, nucleotides and vitamins are the small molecules enzymes and cells consume: NAD, ATP, a vitamin cofactor. Purity, salt form and hydration are the specification, and many are unstable in solution or in the light. The lot is stored as the label says, often cold.

A biochemical is a molecule of life, sold as a reagent: an amino acid, a sugar, a nucleotide, a lipid, an enzyme, an antibiotic. The difference from a bulk chemical is that the use is a biological one, and the impurities that matter are the ones that change that use. An enzyme is specified by activity, not only by mass. An antibiotic is specified by potency. Papers are on PubMed. Structures are on PubChem. Strains and lines that consume these reagents are at ATCC.

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