pCp-Alkyne

pCp-Alkyne is an alkyne-functionalised cytidine bisphosphate derivative supplied at a minimum purity of 95% for RNA labelling and bioconjugation applications. The compound has the empirical formula C₂₉H₅₀N₄O₁₇P₂, a molar mass of 788,67 g/mol and an approximate density of ~1 g/cm³. Its terminal alkyne handle is designed for copper-catalysed or strain-promoted click reactions, enabling selective attachment of fluorophores, affinity tags or other reporter groups after enzymatic ligation to RNA termini. Packaged as a 20 µl plastic unit, it suits focused experimental series, protocol optimisation and reagent-conscious laboratory use. Available from manufacturer Carl ROTH, pCp-Alkyne supports chemical biology, transcript analysis and probe-development programmes that rely on site-selective RNA modification. The stated purity and molar mass facilitate accurate stoichiometry calculations and documentation in research records. Employ standard laboratory controls for phosphorylated nucleoside reagents, including appropriate personal protective equipment and institutional safety procedures during storage, thawing and reaction setup.

This article is part of Click chemistry, bioconjugation & synthesis reagents, in Organic chemicals & synthesis reagents.

Key features

• Appearance: colorless to slightly yellow solution in water
• Purity (HPLC): ≥95 %
• pH: 7.0-8.0
• Pack size: 20 µl plastic
• Purity: min. 95%
• Empirical formula: C₂₉H₅₀N₄O₁₇P₂
• Molar mass: 788,67 g/mol
• Density: ~1 g/cm³
• Storage temperature: -20 °C
• UNSPSC: 12352208
• Technical Information Sheet:
• Safety Data Sheet: