Description
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a protected uridine nucleoside with CAS number 81246-80-2 and empirical formula C₃₆H₄₄N₂O₈Si. The molar mass is 660,83 g/mol. Protection at the 2'-position by a tert-butyldimethylsilyl group and at the 5'-position by a dimethoxytrityl (DMT) moiety yields a versatile intermediate for RNA oligonucleotide synthesis and related nucleic-acid chemistry. Researchers working on antisense, siRNA or diagnostic oligonucleotide platforms can employ this uridine building block in automated or manual phosphoramidite routes. The product is available from manufacturer Carl ROTH within the biochemicals portfolio and supports reproducible laboratory workflows where defined protecting-group patterns are essential. Its molecular identity facilitates controlled detritylation and subsequent chain elongation steps. Handle the material according to standard practices for protected nucleoside reagents in synthetic organic and biochemical laboratories.
This article is part of Coenzymes, nucleotides & vitamins, in Biochemicals & reagents.
Key features
- Purity (HPLC): ≥ 98 %
- Colour: white to off-white
- Form: powder to crystalline powder
- ¹H-NMR Spectrum: corresponds to assigned structure
- CAS number: 81246-80-2
- Pack sizes: 2 g, 5 g, 10 g, 25 g
- Empirical formula: C₃₆H₄₄N₂O₈Si
- Molar mass: 660,83 g/mol
- Storage temperature: +2 to +8 °C
- Weight: 0,013 kg
- Technical Information Sheet:
- Safety Data Sheet:
Compliance & Safety Information
WarningHazard Statements (H-Phrases)
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Questions about 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-ur, idine, 2 g
What is this article?
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-ur, idine, 2 g is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Coenzymes, nucleotides & vitamins, inside Biochemicals & reagents, in Microbiology lab supplies.
Coenzymes, nucleotides and vitamins are the small molecules enzymes and cells consume: NAD, ATP, a vitamin cofactor. Purity, salt form and hydration are the specification, and many are unstable in solution or in the light. The lot is stored as the label says, often cold.
A biochemical is a molecule of life, sold as a reagent: an amino acid, a sugar, a nucleotide, a lipid, an enzyme, an antibiotic. The difference from a bulk chemical is that the use is a biological one, and the impurities that matter are the ones that change that use. An enzyme is specified by activity, not only by mass. An antibiotic is specified by potency. Papers are on PubMed. Structures are on PubChem. Strains and lines that consume these reagents are at ATCC.
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