Description
Acetonitrile ROTISOLV® is a high-purity solvent grade with a minimum assay of 99,9 %, specified for DNA synthesis and controlled to a maximum of 10 ppm H₂O. It is identified by CAS number 75-05-8, EG number 200-835-2 and the empirical formula C₂H₃N, with a molar mass of 41,05 g/mol. Key physical data include a density of 0,79 g/cm³, flash point of 2 °C and boiling point of 81,65 °C, supporting safe process design and solvent handling. Supplied in a 2,5 l pack, this quality is intended for oligonucleotide and DNA synthesis workflows where low water content and high chemical purity are critical to coupling efficiency and product integrity. The ROTISOLV® specification from manufacturer Carl ROTH addresses demanding organic and biomolecular applications beyond general laboratory use. Laboratories engaged in solid-phase DNA chemistry, anhydrous organic reactions and related synthesis can rely on the defined water limit and assay. The larger volume unit suits continuous or high-throughput synthesis set-ups that require a consistent acetonitrile supply.
This article is part of Analytical grade solvents (p.a.), in Solvents.
Key features
- Assay (GC): ≥99,9 %
- Water (KF): ≤0,001 %
- Non volatile matter: ≤0,0001 %
- CAS number: 75-05-8
- Pack size: 2,5 l
- EG nr.: 200-835-2
- Purity: min. 99,9 %, max. 10 ppm H₂O
- Empirical formula: C₂H₃N
- Molar mass: 41,05 g/mol
- Technical Information Sheet:
- Safety Data Sheet:
Compliance & Safety Information
Danger
Hazard Statements (H-Phrases)
Precautionary Statements (P-Phrases)
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Questions about Acetonitrile ROTISOLV®, min. 99.9 %, for DNA synthesis, max. 10 ppm H2O
What is this article?
Acetonitrile ROTISOLV®, min. 99.9 %, for DNA synthesis, max. 10 ppm H2O is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Analytical grade solvents (p.a.), inside Solvents, in Lab chemicals.
An analytical-grade solvent, often marked p.a., has impurity limits tight enough for classical analysis and for preparing reagents. It is not automatically low enough in UV absorbance for HPLC, and it is not dry enough for a water-sensitive reaction. The grade is the purchase.
A solvent dissolves. The grade says which impurities are low enough for the method. Analytical grade is the ordinary pure solvent. HPLC and LC-MS grades limit the absorbance and the ions that would become peaks or background. A dry solvent has had water removed. A deuterated solvent is for NMR, where the hydrogen signal would otherwise drown the sample. Technical grade is for cleaning and for synthesis that does not need a chromatogram. Identity is on PubChem. Names follow IUPAC. Hazards follow ECHA, the CLP Regulation and REACH.
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Shelves beside this one are HPLC & LC-MS grade solvents, Dry & deuterated solvents (NMR, synthesis), Technical & synthesis grade solvents and Green & alternative solvents.
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