Description
DBCO-PEG4-biotin is a biotinylation reagent for copper-free click chemistry, supplied at minimum 95 % purity with CAS number 1255942-07-4 and empirical formula C₃₉H₅₁N₅O₈S. Its molar mass is 749,9 g/mol. A dibenzocyclooctyne (DBCO) group enables strain-promoted azide–alkyne cycloaddition, while the biotin moiety provides high-affinity binding to streptavidin or avidin; a PEG4 spacer improves solubility and reduces steric constraints during conjugation and capture. This serves research laboratories performing bioconjugation, surface labelling, pull-down assays, and detection of azide-modified biomolecules under mild SPAAC conditions. The combination of DBCO reactivity and biotin affinity makes the reagent suitable for organic chemistry and chemical-biology workflows that require selective, copper-free tagging. Offered from manufacturer baseclick, it integrates readily into established click-chemistry protocols. Follow customary laboratory safety measures for reactive organic compounds and review the safety data sheet before use.
This article is part of Coenzymes, nucleotides & vitamins, in Biochemicals & reagents.
Key features
- Appearance: white to grey amorphous solid
- Purity (HPLC): ≥95 %
- CAS number: 1255942-07-4
- Pack sizes: 5 mg, 10 mg
- Purity: min. 95 %
- Empirical formula: C₃₉H₅₁N₅O₈S
- Molar mass: 749,9 g/mol
- Storage temperature: -20 °C
- Technical Information Sheet:
- Safety Data Sheet:
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Questions about DBCO-PEG4-biotin, min. 95 %, 5 mg, plastic
What is this article?
DBCO-PEG4-biotin, min. 95 %, 5 mg, plastic is the article on this page. Luminix Health distributes baseclick for laboratory use. It sits in Coenzymes, nucleotides & vitamins, inside Biochemicals & reagents, in Microbiology lab supplies.
Coenzymes, nucleotides and vitamins are the small molecules enzymes and cells consume: NAD, ATP, a vitamin cofactor. Purity, salt form and hydration are the specification, and many are unstable in solution or in the light. The lot is stored as the label says, often cold.
A biochemical is a molecule of life, sold as a reagent: an amino acid, a sugar, a nucleotide, a lipid, an enzyme, an antibiotic. The difference from a bulk chemical is that the use is a biological one, and the impurities that matter are the ones that change that use. An enzyme is specified by activity, not only by mass. An antibiotic is specified by potency. Papers are on PubMed. Structures are on PubChem. Strains and lines that consume these reagents are at ATCC.
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