Description
Fmoc-L-proline pentafluorophenyl ester is an activated, Fmoc-protected proline derivative supplied at a minimum purity of 95 % for peptide synthesis and related coupling chemistry. It is identified by CAS number 86060-90-4, empirical formula C₂₆H₁₈F₅NO₄, and molar mass 503,42 g/mol. Reported thermal data include a flash point of 300,5 °C and a boiling point of 573,3 °C, which assist laboratory risk assessment and process documentation. The pentafluorophenyl ester activates the carboxyl group of Fmoc-L-proline, facilitating efficient amide-bond formation in solid-phase or solution-phase peptide assembly. Proline residues influence backbone conformation and secondary structure, so a reliable activated form is valuable for constructing constrained peptides, turn motifs, and proline-rich sequences. Chemists and biochemists can incorporate the reagent into multi-residue sequences, fragment couplings, and exploratory peptide design while citing the stated purity, CAS identity, formula, and molar mass in experimental records and material specifications.
This article is part of Click chemistry, bioconjugation & synthesis reagents, in Biochemicals & reagents.
Key features
- Purity (GC): reported (%)
- Purity (HPLC): reported (%)
- IR-spectrum: corresponds to reference spectrum
- pH value: reported ()
- Assay (TLC): reported (%)
- Content (acidim.): reported (%)
- Assay: reported (%)
- Melting point: reported (°C)
- Colour: reported
- Form: reported
- CAS number: 86060-90-4
- Pack sizes: 1 g, 2 g, 5 g
- Purity: min. 95 %
- Empirical formula: C₂₆H₁₈F₅NO₄
- Flash point: 300,5 °C
- Boiling point: 573,3 °C
- Technical Information Sheet:
- Safety Data Sheet:
Compliance & Safety Information
Warning
Hazard Statements (H-Phrases)
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Questions about Fmoc-L-proline pentafluorophenyl ester, min. 95 %, 1 g
What is this article?
Fmoc-L-proline pentafluorophenyl ester, min. 95 %, 1 g is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Click chemistry, bioconjugation & synthesis reagents, inside Biochemicals & reagents, in Microbiology lab supplies.
Click and bioconjugation reagents join two molecules under mild conditions, often an azide to an alkyne, or an NHS ester to an amine. The linker length and the reactive group are the specification. They are small bottles of a reactive compound, and moisture often ruins them.
A biochemical is a molecule of life, sold as a reagent: an amino acid, a sugar, a nucleotide, a lipid, an enzyme, an antibiotic. The difference from a bulk chemical is that the use is a biological one, and the impurities that matter are the ones that change that use. An enzyme is specified by activity, not only by mass. An antibiotic is specified by potency. Papers are on PubMed. Structures are on PubChem. Strains and lines that consume these reagents are at ATCC.
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