Description
tert-Butyldimethylsilyl chloride is a widely used silylating reagent supplied at a minimum purity of 95 % for organic synthesis and protecting-group chemistry. It is identified by CAS number 18162-48-6 and the empirical formula C₆H₁₅ClSi, with a molar mass of 150,73 g/mol and a density of 0,94 g/cm³. The boiling point is 126,4 °C and the flash point is 22 °C, parameters that guide safe laboratory handling. Available in a 1 kg pack from manufacturer Carl ROTH, this chloride enables introduction of the tert-butyldimethylsilyl (TBS) group onto alcohols and related nucleophiles under controlled conditions. Its established physical profile supports reproducible silylation protocols in medicinal chemistry, natural-product synthesis, and fine-chemical manufacture. Research and production laboratories rely on consistent quality when preparing protected intermediates or scaling multi-step sequences. Careful attention to flammability and moisture sensitivity is recommended during storage and use. The defined purity specification together with practical bulk packaging makes the material suitable for both method development and larger preparative work.
This article is part of Inorganic salts, in Inorganic chemicals.
Key features
- Colour: white
- Form: crystals
- Purity (NMR): ≥95 %
- CAS number: 18162-48-6
- Pack sizes: 1 kg, 2 kg, 5 kg
- Purity: min. 95 %
- Molar mass: 150,73 g/mol
- Density: 0,94 g/cm³
- Boiling point: 126,4 °C
- UNSPSC: 12352200
- Technical Information Sheet:
- Safety Data Sheet:
Compliance & Safety Information
Danger
Hazard Statements (H-Phrases)
Precautionary Statements (P-Phrases)
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Questions about tert-Butyldimethylsilyl chloride
What is this article?
tert-Butyldimethylsilyl chloride is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Inorganic salts, inside Inorganic chemicals, in Lab chemicals.
An inorganic salt is an ionic solid, a chloride, a sulfate, a nitrate, a phosphate. The degree of hydration changes the mass that contains one mole of the ion. Analytical grade limits the foreign ions. A hydrate and the anhydrous salt are not interchangeable by weight.
An inorganic chemical is a salt, an acid or base in solid form, a metal, an oxide, or an element. The waters of hydration are part of the formula: a hydrate and an anhydrous salt are different masses for the same ion. Trace metals matter when the salt will be used in analysis. Nanomaterials add particle size to the specification. Look the substance up on PubChem. Hazard classes are on ECHA, under the CLP Regulation and REACH. Transport of the dangerous ones is explained by the UNECE.
Which category should I open next?
The category is Inorganic chemicals. The sub-category is Inorganic salts. The catalogue is Lab chemicals.
Shelves beside this one are Metals, elements & oxides and Nanomaterials & quantum dots.
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