Description
UHPLC Guard Columns NUCLEODUR® PFP featuring 1,8 µm particles in a 4 x 2 mm format shield ultra-high-performance liquid chromatography columns from particulates and strongly retained matrix components. Pentafluorophenyl (PFP) selectivity complements aromatic, halogenated, and polar-aromatic analytes through π–π, dipole, and hydrophobic interactions, making the phase useful when conventional C18 protection is less appropriate. The sub-2 µm packing supports high-efficiency UHPLC conditions while the short guard geometry limits extra-column volume. Each unit pack holds 3 pc(s) and weighs 0,019 kg, convenient for method scouting and continuous analytical runs. These NUCLEODUR® guards from manufacturer MACHEREY-NAGEL follow the same silica platform widely used in UHPLC laboratories. The narrow 4 x 2 mm cartridge installs on standard UHPLC systems and helps preserve the lifetime and performance of matching PFP analytical columns. Laboratories handling pharmaceuticals, metabolites, or other aromatic-rich samples can deploy the set to reduce downtime caused by column fouling without altering established PFP method chemistry.
This article is part of HPLC guard columns, in HPLC columns & accessories.
Key features
- Pack size: 3 pc(s)
- Product type: UHPLC guard column
- Stationary phase: PFP
- Particle size: 1,8 µm
- Dimensions: 4 x 2 mm
- Weight: 0,019 kg
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Questions about UHPLC Guard Columns NUCLEODUR®, PFP, 1.8µm, 4x2mm, 3 unit(s)
What is this article?
UHPLC Guard Columns NUCLEODUR®, PFP, 1.8µm, 4x2mm, 3 unit(s) is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatography equipment.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
What should I check before I order?
The technical information on this page is the manufacturer's sheet. Read that, not a rewritten specification.
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.