Description
Leupeptin hemisulphate, min. 96,5 %, for biochemistry, Molar mass (M) 475,99 g/mol, Storage temp. -20 °C, CAS No. 103476-89-7, Empirical formula C20H38N6O4 · 0,5 H2SO4
Leupeptin competitively inhibits calpain, cathepsin B, kallikrein, papain, plasmin and trypsin. Inhibition of thrombin is controversely discussed. Little or non-inhibiting for pepsin, cathepsin A and D and chymotrypsin.
Directions for use
Working concentration: 0.5-50 µg/ml (1-100 µM). Working solutions are stabile only for few hours. Due to its aldehyde groups, leupeptin may interfere with protein detection assays (e.g. Bradford).