Description
EC 4/3 NUCLEOSIL 100-3 C18 NAUTILUS is an HPLC guard column (pre-column) that shields analytical HPLC columns from particulates and matrix contaminants. The cartridge measures 4 mm in length with a 3 mm internal diameter and is filled with the NUCLEOSIL 100-3 C18 NAUTILUS phase. It is intended for main columns with 3, 4 or 4,6 mm internal diameter and must be mounted in the Column Protection System guard-column holder (REF 718966). Delivered as a pack of three pieces from manufacturer Macherey-Nagel, these EC cartridges help prolong analytical-column lifetime, maintain retention stability and support consistent peak performance in routine HPLC. The C18 NAUTILUS chemistry is suited to reversed-phase separations where polar and non-polar interactions are balanced. Using a matching guard format preserves the selectivity of the main NUCLEOSIL 100-3 C18 NAUTILUS column while offering a practical, cost-effective protection step for method development, QC and everyday laboratory chromatography.
This article is part of HPLC columns, in HPLC columns & accessories.
Key features
- Pack size: 3 pc(s)
- Product type: HPLC guard column
- Phase: NUCLEOSIL 100-3 C18 NAUTILUS
- Length: 4 mm
- Internal diameter: 3 mm
- EAN: 4046681081040
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Questions about EC 4/3 NUCLEOSIL 100-3 C18 NAUTILUS
What is this article?
EC 4/3 NUCLEOSIL 100-3 C18 NAUTILUS is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatography equipment.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
How does ordering and shipping work?
Luminix Health distributes this article from the heart of Europe. Delivery across Europe, two to five days when in stock. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
Which other categories should I open?
The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

