Description
N-Acetyl-β-D-galactosamine-PEG3-azide is a specialised carbohydrate–PEG building block that combines an N-acetyl-β-D-galactosamine recognition motif with a short triethylene glycol spacer and a terminal azide. Its empirical formula is C₁₄H₂₆N₄O₈ and the molar mass is 378,38 g/mol, giving a well-defined reagent for bioorthogonal conjugation. The azide handle supports copper-catalysed or strain-promoted azide–alkyne cycloaddition, enabling efficient attachment to alkyne- or cyclooctyne-bearing probes, surfaces and biomolecules. The PEG3 linker improves solubility and spacing between the sugar and the ligation site, which is advantageous when constructing glycoprotein mimics or targeted delivery scaffolds. This biochemical is available from manufacturer Carl ROTH for laboratory synthesis and glycoscience workflows. It is intended for research use in biochemical and synthetic organic applications where controlled click chemistry on carbohydrate scaffolds is required.
This article is part of Pharmacopoeia reagents & excipients.
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