Description
Trifluoroacetic anhydride serves as a high-purity derivatisation reagent specifically optimised for gas chromatography applications in analytical laboratories. The compound demonstrates a minimum purity of 99 percent along with the empirical formula C₄F₆O₃, a molar mass of 210.03 grams per mole, a density of 1.501 grams per cubic centimetre and a boiling point of 39.15 degrees Celsius. Laboratories conducting routine GC sample preparation depend on its consistent physical properties to obtain reproducible derivatisation outcomes during organic analysis procedures. The reagent from manufacturer Carl ROTH supports analytical workflows that require precise boiling behaviour and controlled density values throughout sample handling. Its well-defined specifications help reduce variability in chromatographic results across both quality-control operations and research environments. Supplied in 100 gram glass containers, the product offers sufficient material for multiple analytical runs while preserving handling reliability under standard conditions. Research facilities and industrial laboratories appreciate the reagent for its capacity to streamline sample-preparation steps in gas chromatographic separations where high-purity reagents directly affect data quality and overall method robustness in daily use.
This article is part of HPLC & LC-MS grade solvents, in Solvents. See also Analytical grade solvents (p.a.).
Key features
- Appearance: colourless liquid
- Assay (titr.): ≥99 %
- Sulphate (SO4): ≤0,05 %
- Chloride (Cl): ≤0,005 %
- Fluoride (F): ≤0,005 %
- CAS Number: 407-25-0
- Empirical formula: C₄F₆O₃
- Purity: min. 99 %
- Unit quantity: 100 g
- Packaging: glass bottle
- Molar mass: 210.03 g/mol
- Density: 1.501 g/cm³
- Technical Information Sheet:
- Safety Data Sheet:
Compliance & Safety Information

DangerHazard Statements (H-Phrases)
Precautionary Statements (P-Phrases)
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Questions about Trifluoroacetic anhydride, min. 99 %, for GC, 100 g, glass
What is this article?
Trifluoroacetic anhydride, min. 99 %, for GC, 100 g, glass is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in HPLC & LC-MS grade solvents, inside Solvents, in Lab chemicals.
HPLC grade limits the absorbance and the residue that would appear as peaks or baseline drift. LC-MS grade goes further on metal ions and on particles that would suppress a mass spectrum. A solvent that is only analytical grade is a false economy on an LC-MS system.
A solvent dissolves. The grade says which impurities are low enough for the method. Analytical grade is the ordinary pure solvent. HPLC and LC-MS grades limit the absorbance and the ions that would become peaks or background. A dry solvent has had water removed. A deuterated solvent is for NMR, where the hydrogen signal would otherwise drown the sample. Technical grade is for cleaning and for synthesis that does not need a chromatogram. Identity is on PubChem. Names follow IUPAC. Hazards follow ECHA, the CLP Regulation and REACH.
Which category should I open next?
The category is Solvents. The sub-category is HPLC & LC-MS grade solvents. The catalogue is Lab chemicals.
Shelves beside this one are Analytical grade solvents (p.a.), Dry & deuterated solvents (NMR, synthesis), Technical & synthesis grade solvents and Green & alternative solvents.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
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Luminix Health distributes this article from the heart of Europe. Delivery across Europe, two to five days when in stock. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

