Description
EC 4/3 NUCLEOSHELL RP 18, 5 µm is an HPLC guard column for protecting analytical main columns in reversed-phase separations. Each cartridge is 4 mm long with a 3 mm internal diameter and contains 5 µm NUCLEOSHELL RP 18 packing, forming a short protective bed upstream of the analytical column. The product is supplied in packs of three and is specified for main columns with 3,4 mm or 4,6 mm internal diameter. Use requires the Column Protection System guard-column holder (REF 718966) to ensure correct seating and a defined flow connection. Matching particle size and RP 18 selectivity help intercept particulates and highly retained matrix components, reducing contamination of the main column and supporting reproducible chromatography. From manufacturer Macherey-Nagel, the EC 4/3 geometry fits standard analytical HPLC systems that employ NUCLEOSHELL RP 18 phases and need compact, replaceable precolumn protection. Laboratories running routine reversed-phase methods can integrate these guard columns to extend main-column lifetime while maintaining method consistency between the protective and analytical stages.
This article belongs on HPLC guard columns, in HPLC columns & accessories.
Key features
- Pack size: 3 pc(s)
- Length: 4 mm
- Inner diameter: 3 mm
- Particle size: 5 µm
- Stationary phase: NUCLEOSHELL RP 18
- EAN: 4046681055119
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Questions about EC 4/3 NUCLEOSHELL RP 18, 5 µm
What is this article?
EC 4/3 NUCLEOSHELL RP 18, 5 µm is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatographie.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatographie.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
What should I check before I order?
When this page shows a safety data sheet, use that manufacturer file. Hazard text does not belong in the sales description. For a pack size, a grade or a certificate that is not on the page, send a quote request or contact the team.
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Luminix Health distributes this article from the heart of Europe. Articles in stock ship within 2–5 business days. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. The full brand index is on shop by brand. Who we are is on about us.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

