Ultrafiltration & concentrators

A common rule of thumb: choose an MWCO two to three times smaller than the molecular weight of the molecule you want to retain. A lower MWCO gives higher recovery but slower filtration. Check the MWCO in kDa on the product page. Many devices contain glycerine to protect the membrane; rinse before first use as the instructions describe. For buffer exchange in larger volumes, compare with dialysis tubing and devices. For a quote or a second opinion, write to sales@luminixhealth.com.

PES offers fast flux, low protein binding and a wide pH range, which makes it a common default. Regenerated cellulose has very low binding and good resistance to many solvents. CTA, cellulose triacetate, also binds little and is intended for aqueous solutions. If recovery of a scarce protein matters most, compare binding data on the product pages in ultrafiltration and concentrators. Questions about a specific product? Contact sales@luminixhealth.com.

Centrifugal concentrators handle microlitres up to small volumes in an ordinary centrifuge, with a suitable rotor. A stirred cell with a flat membrane handles tens to hundreds of millilitres under gas pressure. Tangential or crossflow cassettes handle litres and need a pump. Choose by volume and how often you run it. Stirred cells need a gas supply, usually nitrogen, to apply the pressure. See rotors and peristaltic and dosing pumps. Unsure which one fits? Ask sales@luminixhealth.com.

Concentrating reduces the volume: solvent and small molecules pass through the membrane while your target molecule stays behind. Diafiltration adds fresh buffer during concentration to wash out salts or small molecules, which amounts to a buffer exchange. It is a faster alternative to dialysis for many samples. Both steps can run in one device. For the classic route, see dialysis tubing and devices. Need advice for your set-up? Mail sales@luminixhealth.com.

An ultrafiltration device holds back macromolecules above a stated molecular-weight cutoff and passes salts and water. It concentrates a protein or exchanges its buffer. The cutoff, the volume and whether it is a centrifugal device or a stirred cell are the specification. A 0.2 µm syringe filter does not do this.

Filtration holds back what is larger than the pores and lets the rest through. Paper is the ordinary laboratory filter. A membrane has a stated pore size and a polymer that must survive the solvent. A syringe filter is that membrane in a housing on a syringe. Glass fibre takes a higher dirt load. Ultrafiltration holds back macromolecules and passes salts. The pore size, the chemical compatibility and the volume are the three choices. Laboratory apparatus around filtration is indexed under ISO laboratory apparatus.

This shelf belongs to Filtration, inside Lab consumables. Luminix Health distributes this range for laboratory use.

The neighbouring shelves are Filter paper, Sintered glass filter plates & discs, Syringe filters, Filter cartridges & capsules, Membrane filters, Glass & quartz fibre filters, Bottle-top & vacuum filtration units, Filtration accessories, Extraction thimbles and Dialysis tubing & devices. The category above this shelf is Filtration.

Luminix Health distributes this range from the heart of Europe. We deliver across the EU in two to five days if in stock. Standard delivery is free from €250 excl. VAT. Cold-chain goods and dangerous goods under ADR are never included in that free delivery. The terms are in the Shipping Policy. Send a quote request, contact the team, or read who we are. The full brand index is on shop by brand.

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