Description
Guard column holder C is a dedicated accessory for separate mounting of 21 × 4 mm Valco-type HPLC guard columns. It provides a secure mechanical interface so that short precolumn cartridges can be installed independently of the analytical column, simplifying exchange during routine HPLC maintenance. The holder is dimensioned for the 21 mm length and 4 mm internal-diameter Valco guard format and supports stable fluidic connection in standard liquid-chromatography systems. Supplied as a single unit, it is intended for laboratories that protect analytical columns with replaceable guard cartridges of this size. This holder from manufacturer Macherey-Nagel complements matching VA 21/4 guard columns and helps keep the separation path clean by allowing quick cartridge replacement without disturbing the main column. Compact packaging and a focused design make it a practical hardware component for ion-exchange, organic-acid, and other HPLC methods that rely on Valco-style 21 × 4 mm guards. Use it wherever a reusable holder for this cartridge geometry is required.
This article is part of HPLC guard columns, in HPLC columns & accessories.
Key features
- Pack size: 1 pc
- Product type: HPLC guard column holder
- Holder type: C
- Compatible guard format: 21 × 4 mm Valco-type
- EAN: 4046681083068
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Questions about Guard column holder C
What is this article?
Guard column holder C is the article on this page. Luminix Health distributes Macherey-Nagel for laboratory use. It sits in HPLC guard columns, inside HPLC columns & accessories, in Chromatography equipment.
A guard column is a short column of the same phase as the analytical column, placed in front of it to catch particles and compounds that would stick forever. It is meant to be replaced. A guard of a different phase changes the separation. The holder and the cartridge are often separate parts.
An HPLC column is a tube packed, or coated, with a stationary phase. The sample is carried through it by a liquid, and the compounds leave at different times. The phase, the particle size, the length and the internal diameter decide the separation. A guard column is a short sacrificial piece in front of the analytical column. Fittings and tubing have a bore that either preserves the peak or smears it. Compound names follow IUPAC. Data are on PubChem. Method grades often cite the European Pharmacopoeia or USP.
Which category should I open next?
The category is HPLC columns & accessories. The sub-category is HPLC guard columns. The catalogue is Chromatography equipment.
Shelves beside this one are HPLC columns, HPLC fittings, tubing & inline filters and HPLC accessories.
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.

