Description
TRIS (ROTI®Pharm Excipient) is a high-purity pharmaceutical excipient with a minimum assay of 99 %, conforming to Ph.Eur. and USP requirements. Identified by CAS number 77-86-1 and the empirical formula C₄H₁₁NO₃, it has a molar mass of 121,14 g/mol, a density of 1,32 g/cm³ and a boiling point of 288 °C. The material is available from manufacturer Carl ROTH within the ROTI®Pharm Excipient range, supporting buffering and process applications that rely on defined purity and documented specifications. Its clear physical data and dual Ph.Eur./USP compliance help laboratories and manufacturers maintain consistent quality when preparing buffers, media and other controlled preparations. size suits both routine bench use and larger-scale compounding workflows that require a reliable TRIS source with traceable pharmacopoeial status.
This article is part of Biological buffers (Tris, HEPES, MOPS), in Buffers & pH solutions.
Key features
- Appearance: white crystals or white crystal powder
- Assay (titr.): 99.0-100.5 %
- pH value (5 %, hydrous sol.): 10.0-11.5
- Appearance of solution: clear and colourless
- Melting point: 168-172 °C
- Loss on drying (105 °C): ≤0.5 %
- Water (KF): ≤0.2 %
- Related substances: ≤1.0 %
- Sulphated ash: ≤0.1 %
- Chloride (Cl): ≤0.01 %
- CAS number: 77-86-1
- Pack sizes: 1 kg, 5 kg, 25 kg
- EG nr.: 201-064-4
- Purity: min. 99 %, Ph.Eur., USP
- Molar mass: 121,14 g/mol
- Density: 1,32 g/cm³
- Technical Information Sheet:
- Safety Data Sheet:
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Questions about TRIS, ROTI®Pharm Excipient, 1 kg, plastic
What is this article?
TRIS, ROTI®Pharm Excipient, 1 kg, plastic is the article on this page. Luminix Health distributes Carl Roth for laboratory use. It sits in Biological buffers (Tris, HEPES, MOPS), inside Buffers & pH solutions, in Lab chemicals.
Tris, HEPES, MOPS and their relatives hold pH in a range that cells and proteins tolerate, with a pKa near the working pH. The useful range is roughly one unit either side of the pKa. A phosphate buffer and Tris are not interchangeable in a method that names one of them, because the ion itself has effects.
A buffer resists a change in pH when a little acid or base is added. It does that because a weak acid and its conjugate base are both present. A pH buffer used to calibrate a meter has a stated value at a stated temperature. A biological buffer such as Tris or HEPES is chosen because it holds the pH of a living system and does not poison it. Conductivity standards are the sister articles for a conductivity meter. The ions are on PubChem. Electrode calibration practice sits with EURAMET and BELAC.
Which category should I open next?
The category is Buffers & pH solutions. The sub-category is Biological buffers (Tris, HEPES, MOPS). The catalogue is Lab chemicals.
Shelves beside this one are pH buffers & conductivity standards and Buffers (other).
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The seven catalogues are Labware, Lab chemicals, Lab instruments, Lab consumables, Chromatography equipment, Lab safety equipment and Life Science & Microbiology.
